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Eur J Clin Pharmacol ; 19(3): 177-80, 1981 Feb.
Article in English | MEDLINE | ID: mdl-7011819

ABSTRACT

Two groups of 20 patients with no evidence of cardiovascular, hepatic, renal or gastrointestinal failure were treated orally for five days with placebo or SB 7505 100 mg/day. No change was observed in heart rate or blood pressure. Urine output, the excretion of Na, K and Cl, and creatinine clearance were significantly increased.


Subject(s)
Deoxyepinephrine/analogs & derivatives , Dopamine/analogs & derivatives , Kidney/drug effects , Aged , Blood Pressure/drug effects , Body Weight , Clinical Trials as Topic , Deoxyepinephrine/pharmacology , Double-Blind Method , Female , Heart Rate/drug effects , Humans , Male , Middle Aged , Placebos
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