ABSTRACT
A 16-year-old female with cystic fibrosis (CF) presented with an acute respiratory exacerbation during which black flecks were observed in the spontaneously expectorated sputum. The production of this pigmented sputum was subsequently attributed to Exophiala dermatitidis hyphae. Treatment with antibiotics, corticosteroids, and antifungal medications led to an initial resolution of symptoms and clearance of the black pigment from her sputum. However, the patient again presented nine months later with reappearance of the pigmented flecks and concomitant clinical deterioration and was subsequently treated with an extended course of voriconazole. To the authors' knowledge, this is the first case report of fungal colonization by E. dermatitidis presenting as black flecks spontaneously expectorated in CF sputum.
Subject(s)
Cystic Fibrosis/microbiology , Exophiala/isolation & purification , Lung Diseases, Fungal/diagnosis , Mycoses/diagnosis , Sputum/microbiology , Adolescent , Adrenal Cortex Hormones/therapeutic use , Antifungal Agents/therapeutic use , Cystic Fibrosis/drug therapy , Female , Humans , Lung Diseases, Fungal/drug therapy , Lung Diseases, Fungal/microbiology , Mycoses/drug therapy , Mycoses/microbiology , Pyrimidines/therapeutic use , Recurrence , Triazoles/therapeutic use , VoriconazoleABSTRACT
Creation of a faculty database is a challenging but worthwhile project. In 2002, librarians at the University of Missouri-Columbia were approached by the School of Medicine to create a database of faculty publications. This article outlines the project and gives special emphasis to the problems of author searching. Discussion items include author searching syntax and providing ideas for how to determine if a publication was written by a particular author.
