Current trends in the management of heart disease in pregnancy.

BACKGROUND: The management of heart disease in pregnancy is highly specialized. Guidelines are based on observational studies. This paper describes our experience of these patients, including adverse cardiac events, adherence to guidelines, and areas of suboptimal management. METHODS: Patients referred to the service between 01/05/1999 and 30/06/2005 were identified using clinic lists and keyword searches in databases. A list of 40 management standards was created from European Society of Cardiology and the Confidential Enquiry into Maternal and Child Health guidelines. Adherence to these was recorded and adverse cardiac events noted. RESULTS: There were 177 pregnancies in 155 women with a mean age of 28+/-6 years. Service referrals increased linearly throughout the study period. Of 131 cardiac pregnancies 101 had congenital heart disease (77.1%). Pulmonary oedema, deteriorating functional class, sustained arrhythmia or cardiac intervention occurred in 13 pregnancies (10.2%), though not always in high risk cases. Management guidelines were largely followed, though areas of suboptimal management included lack of pre-conception advice and inadequate post-partum follow-up. Controversial areas include the use of beta-blockade in coarctation of the aorta and the use of elective Caesarean section in high risk patients. CONCLUSIONS: Cardiac pregnancies are increasing, mainly due to the rise in patients with congenital heart disease. Some patients will experience adverse cardiac events, including low risk patients. Pre-conception advice and post-partum follow-up should be improved. In the absence of prospective studies, management is likely to be driven by observational studies.

NPO during labor. Is there any scientific validation?

Maternal death from pulmonary aspiration of gastric contents has virtually disappeared in the United Kingdom. The one case documented in the most recent triennial report was a woman with multiorgan failure in intensive care and is probably not relevant to the current debate [1]. Although not so well documented, other Western countries seem to be experiencing the same decline in maternal death from this cause. At the same time, the burden of proof is falling increasingly on obstetric anesthesiologists as obstetricians and midwives demand that NPO policies should be rejected, unless anesthesiologists can prove that they are necessary. Without any proof of benefit, many midwives actively encourage eating in women who do not really want to eat. A hospital manager who wants to divert money to other areas of health care might make the same argument about employing less experienced--and therefore cheaper--anesthesiologists or nurse anesthetists on the labor floor. Although no self-respecting obstetric anesthesiologist would accept such a situation, there is still no randomized controlled trial that proves that experienced anesthesiologists reduce maternal mortality. Similarly it is difficult for a mother to comprehend the negligible risk of pulmonary aspiration during labor while her care providers insist that it would be more dangerous for her to cross a busy road! Against a background of conflicting advice from midwives and medical practitioners, the mother is likely to eat if she feels so inclined. Pulmonary aspiration is a rare complication, so even if a light diet in labor became acceptable, it is likely that it would take many years for a subsequent increase in maternal mortality to become apparent. It would be disappointing if mistakes made by a previous generation had to be relearned in the twenty-first century. Increasingly, media-controlled pressure groups dictate health fashions, and the physicians frequently can only stand on the sidelines and advise. Most obstetric anesthesiologists agree that a rigid NPO policy in labor is no longer appropriate and that at least water or ice chips should be allowed. Current evidence suggests that solids and semi-solids should be avoided once a woman is in active labor or requests analgesia. The appropriate advice is to allow a carefully audited introduction of isotonic drinks. These drinks seem to be an effective medium for providing calories while minimizing any increase in gastric volume, and such a policy would be unlikely to reverse the reduction in aspiration that has been achieved over the past 50 years.

Homonymous hemianopia following a triplet pregnancy: post-natal cerebral vasculitis or atypical eclampsia.

A 46-year-old woman with a triplet pregnancy developed seizures, an oculogyric crisis and a homonymous hemianopia post-natally. Abnormal neuroimaging studies and lumbar puncture suggested possible cerebral vasculitis. Treatment with aciclovir and prednisolone resulted in a slow resolution of symptoms. This case highlights the difficulty in distinguishing eclampsia from rarer neurological causes of peripartum seizures.

An evaluation of isotonic "sport drinks" during labor.

UNLABELLED: We compared the metabolic effects of allowing women isotonic "sport drinks" rather than water to drink during labor. The effect of these drinks on gastric residual volume was also evaluated. Sixty women in early labor (cervical dilation <5 cm) were randomized to receive either isotonic sport drinks or water only. Plasma beta-hydroxybutyrate, nonesterified fatty acids, and glucose were measured in early labor and at the end of the first stage of labor. Residual gastric volume was assessed within 45 min of delivery by use of an ultrasound scanner. The incidence and volume of vomiting was recorded. At the end of the first stage of labor, plasma beta-hydroxybutyrate (P = 0.000) and nonesterified fatty acids (P = 0.000) had increased and plasma glucose (P = 0.007) had decreased significantly in the Water-Only group. Gastric antral cross-sectional area after delivery was similar in the two groups. The incidence of vomiting and the volume vomited during labor and within the hour of delivery were also similar. There was no difference between the groups in any maternal or neonatal outcome of labor. In conclusion, isotonic drinks reduce maternal ketosis in labor without increasing gastric volume. IMPLICATIONS: Solid foods may endanger a woman's life if consumed during labor. Isotonic sport fluids were evaluated as a nutritional alternative. Results demonstrate that mothers who have not received parenteral opioids can safely drink isotonic drinks in active labor.