1.
Bioorg Med Chem
; 3(12): 1595-603, 1995 Dec.
Article
in English
| MEDLINE
| ID: mdl-8770384
ABSTRACT
A novel series of tetrahydrobenzodioxinopyrroles has been identified as potent and selective alpha 2-adrenoceptor antagonists. Convergent syntheses have been developed that allowed the preparation of analogues and their enantiomers. A compound of particular interest is the 5-fluoro substituted analogue (fluparoxan).