Subject(s)
Humans , Male , Aged , Spinal Fractures , Spinal Fractures/surgery , Resuscitation , Cardiopulmonary Resuscitation , Pain Management , Inpatients , AnesthesiologyABSTRACT
Objetivo: En los últimos años, se han incrementado significativamente las peticiones de tomografía computada (TC) para la evaluación preoperatoria de los dientes supernumerarios (SN) en niños. El objetivo de nuestro trabajo es describir de forma detallada y concisa los dientes SN, basándonos en los pacientes diagnosticados en nuestro centro. Materiales y métodos: Se realizó un análisis retrospectivo de los estudios de TC maxilofacial, realizados entre los años 2011 y 2015. Recopilamos datos de los pacientes (género y edad), motivos de solicitud y hallazgos tomográficos. Los dientes SN fueron clasificados según la enumeración dental de la Federación Dental Internacional (FDI), describiendo la variable LEOMA (localización, emplazamiento, orientación, morfología y angulación) y las alteraciones asociadas (heterotopia, inclusión, anquilosis u odontoma). Resultados: Se registraron 36 pacientes con 49 SN en total. La petición más frecuente de TC fue la evaluación preoperatoria de los dientes SN (21 casos). En su mayoría, la localización fue mesiodiente (30 SN), posterior respecto al diente más próximo (25 SN), con orientación vertical (19 SN), con morfología rudimentaria cónica (26 SN) y con angulación anteroposterior. Conclusión: La realización de una adecuada descripción de los dientes SN ayuda al radiólogo a redactar un ordenado informe y al cirujano maxilofacial a realizar la planificación preoperatoria.
Purpose: A significant increase has been observed in computed tomography (CT) requests for the pre-operative evaluation of supernumerary teeth (SN) in children. The aim of this work is to describe the SN teeth in a detailed and concise fashion, based on patients diagnosed in our institution. Materials and methods: A retrospective analysis of maxillofacial CT studies was performed during the years 2011 to 2015. Patient data was collected, including gender and age, request data, and CT findings. The SN were classified in accordance with the World Dental Federation (FDI) notation, describing LEOMA variables (location, emplacement, orientation, morphology, and angulation), and the presence of associated disorders (heterotopia, inclusión, ankylosis, or odontoma). Results: The study included 36 patients with a total of 49 SN teeth. The most frequent request was a pre-operative CT evaluation of SN teeth (21 cases). The SN teeth were found in the mesiodens location (30 SN), posterior position in relation to the closest tooth (25 SN), conical rudimentary morphology (26 SN), vertical orientation (19 SN), and anterior-posterior angulation. Conclusion: Providing an adequate description of SN teeth can help the radiologist to write a detailed and concise report and help the maxillofacial surgeon in the pre-operative planning.
ABSTRACT
Objetivos. Analizar qué factores valorados en resonancia magnética (RM) y anatomopatológicos de los tumores triple negativo (TN) se relacionan con la recidiva tumoral y con una menor supervivencia libre de enfermedad. Valorar la supervivencia y las recidivas en función de la presencia de componente in situ (CIS). Material y métodos. Estudio retrospectivo de las RM realizadas desde 2007 a 2014, con inclusión de 122 mujeres con cáncer de mama TN y RM de estadificación. En RM se valoraron las características morfológicas (tamaño, márgenes, morfología y señal interna en secuencia T2) y dinámicas (perfusión y difusión). Se estudiaron también los factores anatomopatológicos (Ki67, p53, CK5/6, grado nuclear y Scarff-Bloom) y se analizó la presencia de CIS y el grado tumoral (alto o no alto grado). Se compararon las distintas variables con la presencia de recidiva y se realizó estudio de supervivencia. Resultados. El realce no nodular presentó mayor porcentaje en el grupo de recidivas, y la diferencia fue estadísticamente significativa (p=0,038) y se relacionó con una menor supervivencia libre de enfermedad (p=0,023). La restricción a la difusión (p=0,079) y el ki67 (p=0,052) no asociaron un peor pronóstico. Se detectó CIS en el 44% de los TN, con mayor proporción en el grupo de recidiva, sin relación con una menor supervivencia (p = 0,185). Conclusión. El realce no nodular demostró ser un factor de peor pronóstico. La restricción a la difusión, el ki67 y la presencia de CIS no se asociaron a una menor supervivencia libre de enfermedad (AU)
Objectives. To analyze what factors in magnetic resonance imaging (MRI) and histological study of triple-negative breast cancers are related to tumor recurrence and to shorter disease-free survival. To analyze survival and recurrence in function of the presence of an in situ component. Material and methods. This was a retrospective study of MRI staging examinations in 122 women with triple-negative breast cancer done from 2007 through 2014. In the MRI, we evaluated morphological variables (size, margins, morphology, internal signal in T2-weighted sequences) and dynamic variables (perfusion and diffusion). In the histological study, we evaluated Ki67, p53, CK5/6, nuclear grade, and Scarff-Bloom grade, as well as the presence of an in situ component and tumor grade (high grade or not high grade). We compared the variables between patients with tumor recurrence and those without, and we conducted a survival analysis. Results. Non-nodular enhancement was more common in patients with tumor recurrence (p=0.038) and was associated with shorter disease-free survival (p=0.023). Neither diffusion restriction (p=0.079) nor ki67 (p=0.052) was associated with a worse prognosis. An in situ component was detected in 44% of triple-negative tumors, and a greater proportion of patients in the group with tumor recurrence had an in situ component; however, the presence of an in situ component was not associated with shorter survival (p = 0.185). Conclusion. Non-nodular enhancement was associated with a worse prognosis. Diffusion restriction, ki67, and the presence of an in situ component were not associated with shorter disease-free survival (AU)
Subject(s)
Humans , Female , Breast Neoplasms/pathology , Breast Neoplasms , Triple Negative Breast Neoplasms/pathology , Triple Negative Breast Neoplasms , Prognosis , Carcinoma in Situ/pathology , Carcinoma in Situ , Magnetic Resonance Imaging/methods , Magnetic Resonance Spectroscopy/methods , Retrospective Studies , Perfusion/methods , Ki-67 Antigen/analysis , Ki-67 Antigen/radiation effects , Tumor Suppressor Protein p53/analysis , Tumor Suppressor Protein p53/radiation effects , Immunohistochemistry/methodsABSTRACT
OBJECTIVES: To analyze what factors in magnetic resonance imaging (MRI) and histological study of triple-negative breast cancers are related to tumor recurrence and to shorter disease-free survival. To analyze survival and recurrence in function of the presence of an in situ component. MATERIAL AND METHODS: This was a retrospective study of MRI staging examinations in 122 women with triple-negative breast cancer done from 2007 through 2014. In the MRI, we evaluated morphological variables (size, margins, morphology, internal signal in T2-weighted sequences) and dynamic variables (perfusion and diffusion). In the histological study, we evaluated Ki67, p53, CK5/6, nuclear grade, and Scarff-Bloom grade, as well as the presence of an in situ component and tumor grade (high grade or not high grade). We compared the variables between patients with tumor recurrence and those without, and we conducted a survival analysis. RESULTS: Non-nodular enhancement was more common in patients with tumor recurrence (p=0.038) and was associated with shorter disease-free survival (p=0.023). Neither diffusion restriction (p=0.079) nor ki67 (p=0.052) was associated with a worse prognosis. An in situ component was detected in 44% of triple-negative tumors, and a greater proportion of patients in the group with tumor recurrence had an in situ component; however, the presence of an in situ component was not associated with shorter survival (p = 0.185). CONCLUSION: Non-nodular enhancement was associated with a worse prognosis. Diffusion restriction, ki67, and the presence of an in situ component were not associated with shorter disease-free survival.
