ABSTRACT
BACKGROUND: A strong correlation between a lower heart rate and survival has been demonstrated in various patient populations. The optimal heart rate for heart transplant patients is still unknown. The aim of our study was to evaluate the association between an early heart rate and survival after heart transplantation. MATERIAL AND METHODS: We retrospectively analysed a group of 330 patients, who underwent heart transplantation in our institution from 1994 to 2014 and complete datasets, including 24-hour heart rate monitoring one month after the heart transplantation. Patients were divided in 2 groups: Group A (n = 278) with the average 24-hour heart rate <90 bpm, and Group B (n = 52) with ≥ 90 bpm. RESULTS: The average period of monitoring was 7.5 ± 5.3 years. No differences in baseline characteristics were observed in both groups of recipients and respective donors. One-year survival in groups A and B was 92 % and 81 %, respectively; 5-year survival was 79 % and 60 %, respectively; and 10-year survival was 66 % and 50 %, respectively (p = 0.001). CONCLUSION: Increased heart rate in the early post-transplant period was significantly associated with a poorer survival rate in patients after heart transplantation (Tab. 2, Fig. 1, Ref. 25).
Subject(s)
Heart Diseases/surgery , Heart Rate , Heart Transplantation , Survival Rate , Adult , Aged , Female , Follow-Up Studies , Humans , Male , Middle Aged , Prognosis , Retrospective Studies , Tissue Donors , Young AdultABSTRACT
We present a case of a 53-year-old woman undergoing successful surgical treatment ofcoarcation restenosis after patch grafting in childhood. Despite the optimal result of the operation, normal left ventricle systolic function and coronary angiogram, majority of symptoms, such as angina and dyspnea, persist 16 months after the intervention. In further investigation, pathological values of left ventricular end-diastolic pressure (LVEDP = 30 mm Hg) and coronary flow reserve (CFR = 1.3) were confirmed, implicating recoarctation to be the unusual cause of cardiac syndrome X.
Subject(s)
Aortic Coarctation/surgery , Aortic Coarctation/physiopathology , Coronary Circulation , Diastole , Electrocardiography , Female , Humans , Middle Aged , Recurrence , Reoperation , Ventricular Function, RightABSTRACT
The authors demonstrate a developmental anomaly of the position of the epiphysis of the hip joint, i.e. its medial shift. They assumed that it will be a pre-arthrotic condition, as other known dysplasias of the hip joint. However, the position was reversed as if the shift of the epiphysis of the head of the femur in a medial direction protected the hip joint from the development of arthrotic changes. In case of a medial shift of the epiphysis of the head of the femur--caput varum prearthrosis is not involved.
