Revisiting Recent Tissue Engineering Technologies in Alveolar Cleft Reconstruction.

Tissue engineering and regenerative medicine have received significant attention in treating degenerative disorders and presented unique opportunities for researchers. The latest research on tissue engineering and regenerative medicine to reconstruct the alveolar cleft has been reviewed in this study. Three approaches have been used to reconstruct alveolar cleft: Studies that used only stem cells or biomaterials and studies that reconstructed alveolar defects by tissue engineering using a combination of stem cells and biomaterials. Stem cells, biomaterials, and tissue-engineered constructs have shown promising results in the reconstruction of alveolar defects. However, some contrary issues, including stem cell durability and scaffold stability, were also observed. It seems that more prospective and comprehensive studies should be conducted to fully clarify the exact dimensions of the stem cells and tissue engineering reconstruction method in the therapy of alveolar cleft.

Effect of Intracanal Post Space Treatments on Push-Out Bond Strength of Fiber Posts to Root Dentin.

OBJECTIVES: The main disadvantage of fiber posts is their low bond strength to root canal wall. The aim of the present study was to assess the effect of different root canal post space treatments on push-out bond strength of fiber posts to root canal dentin. MATERIALS AND METHODS: After post space preparation in 40 endodontically treated human premolars, the teeth were randomly divided into four experimental groups: Group 1: control group, group 2: Endsolv R, group 3: ultrasonic cleaning, group 4: Clearfil Repair. Afterwards, the posts were bonded with Panavia F 2.0 bonding cement. The bond strength of fiber posts to root canal wall in the middle part of canal was evaluated following thermocycling using push-out test. Data were analyzed using one-way ANOVA and Tamhane's multiple comparisons test. The failure mode of each group was determined under a stereomicroscope. RESULTS: There was a significant difference in the mean push-out bond strength among the groups (P<0.05). The lowest bond strength was noted in the control group. The control group had significant differences with ultrasonic and Clearfil Repair groups (P<0.05). The bond strength of Endsolv R group increased; however, it was not significant (P>0.05). CONCLUSIONS: It seems that ultrasonic cleaning and Clearfil Repair can modify the root canal wall and significantly increase the bond strength of fiber posts.