ABSTRACT
JGP study shows that ryanodine receptor 3 is important for extraocular muscle function.
Subject(s)
Oculomotor Muscles , Ryanodine Receptor Calcium Release Channel , Animals , Mice , RyanodineABSTRACT
JGP study shows that pro-secretory agonists prompt CFTR to assemble into large lipid platforms.
Subject(s)
Cystic Fibrosis Transmembrane Conductance Regulator , Membrane Microdomains , Membrane LipidsABSTRACT
JGP study finds that mild calcium leak is associated with improved resistance to muscle fatigue.
Subject(s)
Calcium , Muscle Fibers, Skeletal , CytoplasmABSTRACT
JGP paper explores the strength of the hydrogen bond network at the active site of GlpG.
Subject(s)
Endopeptidases , Catalytic Domain , Hydrogen BondingABSTRACT
JGP study examines how a mutation in KCNQ3 affects channel behavior.
Subject(s)
Epilepsy , KCNQ3 Potassium Channel , Affect , Humans , KCNQ2 Potassium Channel , MutationABSTRACT
JGP paper explores how a mutated troponin T causes cardiac hypertrophy.
Subject(s)
Cardiomyopathy, Hypertrophic , Troponin T/genetics , Cardiomegaly , Humans , Kinetics , MutationABSTRACT
JGP study explains how chromomycin A2 affects insulin secretion.
Subject(s)
Insulin-Secreting Cells , Islets of Langerhans , Glucose , Insulin , Insulin Secretion , Phospholipases A2 , Plicamycin/analogs & derivativesABSTRACT
JGP study probes how nebulin affects muscle function.
Subject(s)
Muscle Proteins , Sarcomeres , Actin Cytoskeleton , Muscle, SkeletalABSTRACT
New method predicts the molecular basis of membrane proteins' voltage sensitivity.
Subject(s)
Ion Channel Gating , Membrane ProteinsABSTRACT
Tandem JGP studies investigate how propofol affects voltage-gated sodium channels.
Subject(s)
Propofol , Anesthetics, IntravenousABSTRACT
JGP study explores a new way to conceptualize an enduring neuronal mystery.
Subject(s)
Neuronal Plasticity , NeuronsABSTRACT
JGP paper presents a model for studying cyclic nucleotide-modulated channels.
Subject(s)
Cyclic Nucleotide-Gated Cation Channels , Nucleotides, CyclicABSTRACT
New JGP study uncovers a connection between Connexin 26 fast and slow gates.
Subject(s)
Connexins/genetics , Deafness , Connexin 26 , Humans , MutationABSTRACT
JGP study shows that endocytosis aids synaptic vesicle release at ribbon synapses.
Subject(s)
Synapses , Synaptic Vesicles , EndocytosisABSTRACT
JGP study explores a novel photoreception pathway in a marine mollusk.
Subject(s)
Pecten , Animals , Photoreceptor CellsABSTRACT
JGP study explores diurnal changes in calcium sources governing BK activity in the SCN.
Subject(s)
Circadian Clocks , Action Potentials , Calcium , Large-Conductance Calcium-Activated Potassium Channels , Neurons , Suprachiasmatic NucleusABSTRACT
New JGP study explains how auxiliary proteins relieve polyamine block of AMPARs.
Subject(s)
Polyamines , Receptors, AMPA , ProteinsABSTRACT
JGP study suggests the anion exchanger AE1 operates via an elevator-like mechanism.
Subject(s)
Anion Exchange Protein 1, Erythrocyte , Friends , Anions , Elevators and EscalatorsABSTRACT
New JGP study explores the thermodynamic cycle and cation preference of the sugar symporter MelB.
