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PDA J Pharm Sci Technol ; 56(3): 124-9, 2002.
Article in English | MEDLINE | ID: mdl-12109332

ABSTRACT

Traditional type I glass containers are becoming more unsuitable for packaging modern diagnostics and drugs. When using certain drugs (high-pH formulations, complexing agents, drugs with low dosage, sensitivity to pH-shift or ion release), product degradation can occur, reducing the drug's performance, potency, and shelf-life. To prevent chemical interaction between the container and the content, a coating technology applying a silicon dioxide layer to the internal container surface can bring the solution.


Subject(s)
Drug Packaging/standards , Drug Stability , Glass
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