Axial Spondyloarthritis is associated with changes in lumbosacral loading during daily activities.

BACKGROUND: There is currently little insight in lumbar spine loading during activities of daily living in patients with axial spondyloarthritis. Furthermore, it is unclear how inflammation or ankylosis-related mobility limitations in patients with axial spondyloarthritis affect lumbosacral loading, and if lumbar movement profiles have an effect on lumbosacral loading as well. Therefore, the aim of this study is to get more insight in the differences in peak and cumulative lumbosacral loading in patients with axial spondyloarthritis during activities of daily living. METHODS: Three-dimensional motion analysis with integrative force-plates was used to calculate peak lumbosacral moment (peak loading) and lumbosacral moment impulse (cumulative loading), of 19 patients with axial spondyloarthritis and 23 healthy controls during forward bending, sit-to-stand and two lifting tasks (symmetric/asymmetric). We compared inflammatory (n = 7) and ankylosed (n = 12) patients with axial spondyloarthritis and controls. Patients were also classified into Flexion or Lordotic profile. FINDINGS: Both inflammatory and ankylosed patients generated significantly larger lumbosacral moment impulses than healthy controls in all movements, except during sit-to-stand, where the inflammatory group showed larger moment impulse than both other two groups. Patients with a Lordotic profile showed lowered peak lumbosacral moments and moment impulses compared to those with a Flexion profile. INTERPRETATION: Both inflammatory and ankylosed patients experienced more cumulative loading depending on the activity. But our findings suggest that classification of patients into different movement profiles might be more interesting to clinically target specific loading adaptations related to pain and fear of movement.

Differences in multi-segmental spine kinematics between patients with different stages of axial spondyloarthritis and healthy controls.

BACKGROUND: The effects of inflammation and ankylosis on spinal kinematics of patients with axial spondyloarthritis (axSpA) are poorly understood. Furthermore, existence of (mal)adaptive movement profiles within axSpA, and differences between movement profiles in sensation of pain or fear of movement has never been investigated. OBJECTIVES: To investigate differences in range of motion in six spinal regions and the hips between inflammatory and ankylosed patients with axSpA, and to increase insight in different movement profiles of patients with axSpA and their association with pain and fear. DESIGN: Observational, cross-sectional. METHODS: Three-dimensional motion analysis was performed in 20 patients with axSpA and 23 healthy controls during range of motion tasks in all three planes. We compared patients with inflammatory (n = 8) and ankylosed (n = 12) axSpA, and controls. Patients were also classified into Flexion or Lordotic profile. Questionnaires regarding pain and fear of movement were conducted. RESULTS/FINDINGS: Both inflammatory and ankylosed axSpA patients have limited spinal ROM and reduced movement speed compared to healthy controls. Patients with a Lordotic profile showed significantly less ROM in lumbar regions and experienced more pain during forward bending than patients with a Flexion profile. CONCLUSIONS: Both inflammation and ankylosis contribute to spinal mobility impairment, and axSpA patients with a lordotic profile experienced more pain. This profile may be a maladaptive movement strategy to prevent further pain increase. Suggesting that pain and fear of movement, might be better variables to specify patients' spinal mobility limitations for individual physical therapy and rehabilitation patient profiling.

Multi-segment spine and hip kinematics in asymptomatic individuals during standardized return from forward bending versus functional box lifting.

Clinically, sagittal spinal mobility is objectively assessed by forward bending range of motion (ROM) tests such as the modified-Schober test (m-Schober test). However, evidence comparing ROM during forward bending and daily activities is limited. In this study, a kinematic model including six spinal regions, pelvic/sacral and femur segment was used to characterize associations between m-Schober test and return from forward bending (RFB), and between RFB and lifting. No significant correlations were found between m-Schober test and lumbar ROM during RFB. Furthermore, we found significantly smaller ROM in all spinal regions during lifting compared to RFB, except in the upper thoracic spine, lumbosacral (L5/S1) and hip joints. However, we observed moderate to very strong correlations between the two movements tasks for all lumbar regions. Furthermore, cross-correlation between L5/S1 and lower lumbar spine regions showed no segmental redundancy of L5. These results suggest that an m-Schober test provides insufficient insight into lumbar mobility and that multi-segmental spine measurements should be introduced clinically. Furthermore, this study has demonstrated that RFB can be used as a reference for lumbar regions during lifting, with use of the current multi-segmental spine model and that the inclusion of L5/S1 provides more detailed information on lumbar kinematics.