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Eur Neuropsychopharmacol ; 26(5): 869-76, 2016 05.
Article in English | MEDLINE | ID: mdl-26723168

ABSTRACT

Biological explanations address not only proximal mechanisms (for example, the underlying neurobiology of obsessive-compulsive disorder), but also distal mechanisms (that is, a consideration of how particular neurobiological mechanisms evolved). Evolutionary medicine has emphasized a series of explanations for vulnerability to disease, including constraints, mismatch, and tradeoffs. The current paper will consider compulsive symptoms in obsessive-compulsive and related disorders and behavioral addictions from this evolutionary perspective. It will argue that while obsessive-compulsive disorder (OCD) is typically best conceptualized as a dysfunction, it is theoretically and clinically valuable to understand some symptoms of obsessive-compulsive and related disorders in terms of useful defenses. The symptoms of behavioral addictions can also be conceptualized in evolutionary terms (for example, mismatch), which in turn provides a sound foundation for approaching assessment and intervention.


Subject(s)
Biological Evolution , Compulsive Behavior/physiopathology , Compulsive Personality Disorder/physiopathology , Defense Mechanisms , Models, Neurological , Obsessive-Compulsive Disorder/physiopathology , Psychology, Comparative/methods , Animals , Behavior, Addictive , Behavior, Animal , Combined Modality Therapy , Compulsive Behavior/diagnosis , Compulsive Behavior/psychology , Compulsive Behavior/therapy , Compulsive Personality Disorder/diagnosis , Compulsive Personality Disorder/psychology , Compulsive Personality Disorder/therapy , Diagnostic and Statistical Manual of Mental Disorders , Humans , Obsessive-Compulsive Disorder/diagnosis , Obsessive-Compulsive Disorder/psychology , Obsessive-Compulsive Disorder/therapy , Stress, Psychological/physiopathology , Stress, Psychological/psychology , Substance-Related Disorders/diagnosis , Substance-Related Disorders/physiopathology , Substance-Related Disorders/psychology , Substance-Related Disorders/therapy , Terminology as Topic
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