ABSTRACT
Venous Ulcers (VU) represent 60-80% of all leg ulcers and are the final stage of the disease secondary to venous hypertension or valve insufficiency. Conventional treatment that focuses on its etiological factors continues to be the gold standard; however, 30% of ulcers do not heal with this treatment; thus, it has been seen that the use of growth factor can be used as an adjuvant for this pathology. A literature review was carried out to evaluate the evidence from systematic reviews, meta-analyses, case studies, and quantitative studies that respond to the objective of this analysis review in the different databases with specific inclusion criteria with publications between 2002 and 2022, initially finding the topical application of the factor and later, more recently, the intralesional and perilesional application, the latter being an alternative treatment for this type of pathology and generating some recommendations for using the Factor.
Subject(s)
Hypertension , Leg Ulcer , Varicose Ulcer , Humans , Varicose Ulcer/diagnosis , Varicose Ulcer/drug therapy , Databases, Factual , EGF Family of ProteinsABSTRACT
Se obtuvo la completa recuperación neurológica de un paciente cuadriparético, con la exéresis radical de un ganglioneuroma intrarraquideo de C1 a C3 mediante una laminectomía estándar. El ganglioneuroma es un tumor poco frecuente y de localización generalmente en la región torácica. La asociación de ganglioneuroma y neurofibroma puede encontrarse en la enfermedad de Von Recklinhausen. El pronóstico es favorable cuando se logra la completa resección del tumor, particularmente en lesiones bien encapsuladas.