ABSTRACT
In this article anesthesiologic and hematologic aspects of a patient with Hemophilia-A, who underwent craniotomy for a right middle cerebral artery aneurysm, are discussed.
Subject(s)
Hemophilia A/complications , Intracranial Aneurysm/surgery , Adult , Anesthesia, General , Coagulants/therapeutic use , Craniotomy , Factor VIII/therapeutic use , Hemarthrosis/prevention & control , Hematoma/prevention & control , Hemophilia A/prevention & control , Humans , Male , Monitoring, Intraoperative , Subarachnoid Hemorrhage/surgeryABSTRACT
Complication during a drum catheter placement via an antecubital fossa vein is presented.
Subject(s)
Catheterization, Central Venous/adverse effects , Sternum/surgery , Child , Female , Humans , Medical Errors , Radiography, ThoracicSubject(s)
Calcium Channel Blockers/therapeutic use , Diltiazem/therapeutic use , Dopamine Agents/therapeutic use , Dopamine/therapeutic use , Kidney Transplantation/physiology , Adult , Anastomosis, Surgical , Blood Urea Nitrogen , Calcium Channel Blockers/administration & dosage , Creatinine/blood , Diltiazem/administration & dosage , Dopamine/administration & dosage , Dopamine Agents/administration & dosage , Female , Humans , Infusions, Intravenous , Male , Renal Artery/surgerySubject(s)
Anesthesia, General , Coronary Artery Bypass , Kidney Transplantation , Adult , Diazepam/administration & dosage , Droperidol/administration & dosage , Famotidine/administration & dosage , Fentanyl/administration & dosage , Halothane/administration & dosage , Humans , Isoflurane/administration & dosage , Male , Middle Aged , Morphine/administration & dosage , Pancuronium/administration & dosage , Postoperative Care , Premedication , Vecuronium Bromide/administration & dosageSubject(s)
Anticoagulants/therapeutic use , Cardiac Surgical Procedures , Heparin Antagonists/therapeutic use , Heparin/therapeutic use , Kidney Failure, Chronic/complications , Protamines/therapeutic use , Adult , Anesthesia/methods , Coronary Artery Bypass , Female , Heart Valve Prosthesis Implantation , Humans , Hypothermia, Induced , Intraoperative Care , Kidney Failure, Chronic/therapy , Male , Middle Aged , Patient Selection , Renal Dialysis , Retrospective StudiesABSTRACT
The effects of two calcium channel blockers (verapamil and nicardipine) on indirectly elicited muscle twitch and possible interactions between these drugs and non-depolarising muscle relaxants (vecuronium, atracurium, pancuronium) were investigated using isolated rat phrenic nerve-hemidiaphragm preparations. Both verapamil 10(-5) M and nicardipine 10(-6) M caused significant depression of twitch amplitude. Verapamil significantly increased vecuronium- and atracurium-induced neuromuscular block, but not that produced by pancuronium. Nicardipine potentiated atracurium-induced neuromuscular block but had no effect on pancuronium- and vecuronium-induced twitch depression. Neostigmine 10(-6) M did not produce any significant changes in the maximal recovery of twitch depression induced with calcium channel blockers and muscle relaxants combinations; also, neostigmine had no effect on maximal recovery time of twitch depression.
Subject(s)
Calcium Channel Blockers/pharmacology , Neuromuscular Junction/drug effects , Neuromuscular Nondepolarizing Agents/pharmacology , Animals , Atracurium/pharmacology , Culture Techniques , Dose-Response Relationship, Drug , Drug Interactions , Male , Nicardipine/pharmacology , Pancuronium/pharmacology , Rats , Vecuronium Bromide/pharmacology , Verapamil/pharmacologyABSTRACT
A case of acute severe organophosphate poisoning by deliberate self administration is reported. The patient required intensive therapy for 30 days. Unusual features of the case were the avoidance of atropine, because of the high risk of ventricular fibrillation, and the ineffectiveness of pralidoxime.
