ABSTRACT
We studied 422 patients with urethral discharge recruited from 4 sentinel sites in Morocco to determine sociodemographic characteristics, history of STI infection, infecting organism and antibiotic susceptibility of Neisseria gonorrhoeae. The mean age of the sample was 28 years (range 16-67 years), and most were single, had multiple sex partners without taking protective measures and came from all social backgrounds; 59.9% had a history of a previous STI. The majority (87%) of the infections were the acute form. By polymerase chain reaction of urine samples of 399 patients, 41.6% had N. gonorrhoeae infection, 6.3% Chlamidia trachomatis and 10.8% both organisms; in 41.4% no organism was identified. N. gonorrhoeae was strongly susceptible to ciprofloxacin.
Subject(s)
Chlamydia Infections/epidemiology , Chlamydia Infections/microbiology , Chlamydia trachomatis , Gonorrhea/epidemiology , Gonorrhea/microbiology , Urethral Diseases/epidemiology , Urethral Diseases/microbiology , Acute Disease , Adolescent , Adult , Age Distribution , Chlamydia Infections/diagnosis , Chlamydia trachomatis/genetics , Drug Resistance, Bacterial , Educational Status , Gonorrhea/diagnosis , Humans , Incidence , Marital Status/statistics & numerical data , Microbial Sensitivity Tests , Middle Aged , Morocco/epidemiology , Polymerase Chain Reaction , Prevalence , Recurrence , Residence Characteristics/statistics & numerical data , Risk Factors , Sentinel Surveillance , Sexual Behavior/statistics & numerical data , Socioeconomic Factors , Surveys and Questionnaires , Urethral Diseases/diagnosisABSTRACT
We studied 422 patients with urethral discharge recruited from 4 sentinel sites in Morocco to determine sociodemographic characteristics, history of STI infection, infecting organism and antibiotic susceptibility of Neisseria gonorrhoeae. The mean age of the sample was 28 years [range 16-67 years], and most were single, had multiple sex partners without taking protective measures and came from all social backgrounds; 59.9% had a history of a previous STI. The majority [87%] of the infections were the acute form. By polymerase chain reaction of urine samples of 399 patients, 41.6% had N. gonorrhoeae infection, 6.3% Chlamidia trachomatis and 10.8% both organisms; in 41.4% no organism was identified. N. gonorrhoeae was strongly susceptible to ciprofloxacin
Subject(s)
Acute Disease , Age Distribution , Chlamydia Infections , Chlamydia trachomatis , Drug Resistance, Bacterial , Gonorrhea , Microbial Sensitivity Tests , Polymerase Chain Reaction , Residence Characteristics , Sexual Behavior , Socioeconomic Factors , Urethral DiseasesABSTRACT
BACKGROUND: Blastomycosis is an uncommon chronic granulomatosis caused by Blastomyces dermatitidis. We present a case with a skin localization that disclosed malignant corticoadenoma. CASE REPORT: A 32-year-old man consulted for inflammatory nodules of the face and lower limbs. The histological examination of a nodule biopsy was in favour of blastomycosis. Ketoconazole treatment was ineffective. Amphotericin B provided cure of the skin lesions. Search for extension disclosed a malignant corticoadrenoma. DISCUSSION: Blastomycosis is very rare in Morocco. The portal is usually the lung. Unique skin involvement is very exceptional. To our knowledge this is the first report of a blastomycosis-corticoadenoma association. The clinical situation may be alarming in immunodepressed subjects. Amphotericin B treatment is indicated.
Subject(s)
Adrenal Cortex Neoplasms/diagnosis , Adrenocortical Adenoma/complications , Adrenocortical Adenoma/diagnosis , Blastomycosis/complications , Adrenal Cortex Neoplasms/complications , Adult , Humans , MaleABSTRACT
On the basis of two new cases of cutaneous mucosal tertiary syphilis and a personal series of 30 cases observed at the University Hospital of Rabat and Casablanca from 1963 to 1980, we reviewed the clinical presentations of this disease. Late stage syphilis has not disappeared and appears to be increasing over the last decade. Lesions of the nervous system are increasingly reported in atypical often unrecognized forms. Cutaneous mucosal tertiary syphilis is very rare and little known and can take on the form of skin lesions suggesting tuberculosis, deep mycosis, sarcoidosis, leprosy or leishmaniasis. Based on our experience, we recall the variety of clinical presentations including superficial nodules and deep gommas leading to atrophic and rarely hypertrophic scars. The diagnosis relies essentially on the serology results which are always positive at a significant level. The pathology examination adds no essential information. Rapid response to treatment is one of the important criteria of the diagnosis of syphilis.
Subject(s)
Scalp Dermatoses/pathology , Syphilis, Cutaneous/pathology , Adolescent , Adult , Humans , Male , Nervous System Diseases/etiology , Syphilis, Cutaneous/complicationsABSTRACT
Between 1980 and 1987, 12 systematic surveys were made on a population of 254,979 people, of whom 236,868 were actually examined (92.61%). 422 suspected cases were identified i.e. a global detection rate of 1.66% of which only 241 reported to Aïn-Chock Hospital for further tests (55%). Out of these 241 suspected cases, 217 proved as having leprosy, i.e. a 90% correlation between the clinical suspicion and the biological identification. The 181 suspected cases who never reported to the hospital and the 16 leprosy patients whom we lost sight of constitute as a whole 46.68% of the suspected cases first identified. This shows an obvious lack of coordination between the local Authority and the medical service. The 185 confirmed cases of leprosy are shown in the table below and compared with those of the Central Statistical Office.
Subject(s)
Leprosy/epidemiology , Adolescent , Adult , Child , Female , Humans , Incidence , Leprosy, Lepromatous/epidemiology , Leprosy, Tuberculoid/epidemiology , Male , Mass Screening , Middle Aged , Morocco/epidemiology , Population Surveillance , PrevalenceSubject(s)
Adenoma, Sweat Gland/pathology , Skin Neoplasms/pathology , Adult , Arm , Humans , Male , ThoraxSubject(s)
Sarcoma, Kaposi/immunology , Female , HIV/immunology , Humans , Male , Middle Aged , MoroccoABSTRACT
The authors, in a series of 65 cases of Behçet's disease, notice 53% of rheumatological manifestations which are third in line after aphthosis and ocular disease. In order of decreasing frequency, it concerns arthritis (mono, oligo or poly-arthritis), arthralgias with an almost identical frequency, sacroiliitis, extraarticular involvement. These rheumatological manifestations are readily associated with necrotic pseudo-folliculitis and cutaneous aphthosis.
Subject(s)
Behcet Syndrome/diagnosis , HLA-B Antigens , Joint Diseases/etiology , Adolescent , Adult , Arthritis/etiology , Female , Gene Frequency , HLA Antigens/analysis , Humans , Knee Joint , Male , Middle Aged , Pain/etiology , Recurrence , Sacroiliac Joint , Tendinopathy/etiologySubject(s)
Prostheses and Implants , Retinal Detachment/surgery , Silicone Elastomers , Adolescent , Adult , Female , Humans , Male , Middle AgedSubject(s)
Eye Neoplasms/diagnosis , Retinoblastoma/diagnosis , Adolescent , Child , Child, Preschool , Diagnosis, Differential , Female , Humans , Infant , Infant, Newborn , Male , Time FactorsSubject(s)
Mass Screening , Vision Disorders/prevention & control , Child , Humans , Morocco , School Health ServicesABSTRACT
Ganglioneuroblastoma a transitional tumor of sympathetic origin has not yet been described as involving orbit. It is characterized by a mixture of cells ranging from primitive neuroblast to well differentiated ganglion cells within a neurofibromatous tissue. The prognosis is uncertain, as the tumor may either undergo maturation into a ganglioneuroma or may metastasize widely and rapidly as in neuroblastoma. We may postulate a relationship between ganglioneuroblastoma and Recklinghausen's neurofibromatosis in view of the development of the tumor in conjunction with the phacomatosis.
Subject(s)
Ganglioneuroma/pathology , Neoplasms, Multiple Primary/pathology , Orbital Neoplasms/pathology , Cell Transformation, Neoplastic/pathology , Child, Preschool , Diagnosis, Differential , Ganglioneuroma/physiopathology , Ganglioneuroma/therapy , Humans , Male , Neuroblastoma/pathology , Neuroblastoma/physiopathology , Neurofibromatosis 1/pathology , Orbital Neoplasms/therapy , Prognosis , Skin Neoplasms/pathologyABSTRACT
Cowden's disease is a phacomatosis (multiple hamartomas), which is a familial, hereditary, dominant autosomal affection presenting as typical buccolabial mucocutaneous lesions associated with digestive tract polyps. Differential diagnosis of the predominantly digestive form of the disease is polyposis. A new case of this rare disorder is reported, only 62 cases being documented in literature.
Subject(s)
Hamartoma/genetics , Neoplasms, Multiple Primary/genetics , Adolescent , Colonic Polyps/genetics , Digestive System Neoplasms/genetics , Humans , Intestinal Neoplasms/genetics , Lip/pathology , Male , Mouth Mucosa/pathology , Mouth Neoplasms/genetics , Skin Neoplasms/genetics , SyndromeABSTRACT
The authors report the results obtained in 74 cases, or 105 eyes, with congenital glaucoma operated on by trabeculectomy. Three different trabeculectomy procedures were used: closing the scleral flap with two sutures; placing a silastic passing in bridge under the flap; and tightly suturing the scleral flap. The last mentioned method gave the best results. This was related to intervention during the first phase of the disease and minimizing damage to the cornea. It is derived from this study that the mechanism of action of a trabeculectomy is more an "opening" of the paths of physiological drainage than filtration via the sub-conjunctival space.
Subject(s)
Glaucoma/surgery , Trabecular Meshwork/surgery , Adolescent , Age Factors , Child , Child, Preschool , Female , Follow-Up Studies , Glaucoma/congenital , Humans , Infant , Male , Suture TechniquesABSTRACT
For one year, the authors have observed the clinical and biological development of early syphilis on 205 patients infected between 1971 and 1979 and treated by a single injection of Benzathine-Penicilline of 2,400,000 U.I. The serological negativeness has been obtained in the proportions as follow: - 91,43 p. 100 of primary syphilis (blood test positive), - 88,57 p. 100 of secondary syphilis, - 67,69 p. 100 of latent syphilis. These results compared to those obtained by other more time-consuming and expensive methods, can be considered as satisfactory.
Subject(s)
Penicillin G Benzathine/administration & dosage , Syphilis/blood , Humans , Injections, Intramuscular , Syphilis/drug therapy , Syphilis Serodiagnosis , Syphilis, Latent/bloodABSTRACT
The authors report four cases of methanol poisoning, two of which suffering acute bilateral optic neuropathy which secondarily leads to optic atrophy. The report the main clinical features of such a poisoning and the actual basis of its physiopathology and treatment. According to the four cases reported, they underline the importance of early diagnosis and specific treatment.