Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Publication year range
2.
J Neurol ; 263(9): 1819-27, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27334906

ABSTRACT

Postural instability is a frequent symptom of patients with idiopathic normal pressure hydrocephalus (iNPH), and might be due to the misperception of body verticality. The objective of this study was to assess the usefulness of the subjective body vertical (SBV) as a potential tool for diagnosing iNPH. Twenty patients with iNPH underwent tests of SBV in the pitch and roll planes before and after cerebrospinal fluid (CSF) drainage. Ten patients with other central gait disorders served as controls and also underwent tests for SBV. Before CSF drainage, patients with iNPH showed an impaired verticality perception in the pitch plane with a significant backward deviation of the SBV as compared to the control group (iNPH: mean ± SD -3.7 ± 3.6°; control group: -0.8 ± 2.2°; t value = -2.30, p t-test = 0.03). After CSF drainage, the SBV of the iNPH patients normalized for the pitch plane (-0.9 ± 1.9°). There was a correlation between the backward deviation of the SBV and the ventricular enlargement of the frontal horns (Evan's index; r = -0.52; p Pearson = 0.02). An even stronger correlation was found with the enlargement of the third ventricle (Thalamus index; r = -0.64; p Pearson = 0.002). The new and clinically relevant finding of this study is that verticality perception of patients with iNPH is primarily impaired the pitch plane, and it improves after CSF drainage. This disturbance in pitch might be due to a bilateral central vestibular dysfunction of the thalamus. Determination of the SBV in pitch promises to increase diagnostic accuracy in the cases of suspected iNPH.


Subject(s)
Hydrocephalus, Normal Pressure/diagnosis , Neurologic Examination/methods , Perception , Postural Balance , Proprioception , Accidental Falls , Aged , Biomechanical Phenomena , Cerebrospinal Fluid Shunts , Drainage , Female , Gait Disorders, Neurologic/diagnosis , Humans , Hydrocephalus, Normal Pressure/diagnostic imaging , Hydrocephalus, Normal Pressure/therapy , Male , Neuropsychological Tests , Severity of Illness Index , Third Ventricle/diagnostic imaging
3.
Nervenarzt ; 86(4): 431-9, 2015 Apr.
Article in German | MEDLINE | ID: mdl-25801948

ABSTRACT

BACKGROUND: Slow walking with reduced body dynamics is a characteristic feature of locomotion in the elderly. Impaired mobility and falls associated with gait disorders significantly contribute to a reduced quality of life in the elderly. OBJECTIVES: A gait disorder is not an inevitable consequence of aging. This article shows that it is worth recognizing specific deficits and differentiating specific aspects in multifactorial disorders because many causes can be well treated. Also provided are the bases for clinical classification and therapeutic principles. METHODS: Review of recent literature and clinical review based on own experience and own scientific results. RESULTS: Common causes of disturbed gait in the elderly are neurological deficits, including sensory deficits (e.g. peripheral neuropathy and vestibulopathy), neurodegeneration (e.g. cerebellar ataxia and parkinsonian syndromes, cognitive impairment (e.g. degenerative dementia), degeneration of joints (e.g. coxarthrosis) and general loss of muscle mass (sarcopenia). Furthermore, a fear of falling also contributes to the gait disorder. Multimodal therapies are often necessary and the principles are presented. CONCLUSION: Identification of deficits is a prerequisite for specific therapy. As physical activity protects against cognitive impairment, reduces the risk of falling and improves overall quality of life, a structured assessment of causes for gait impairment is crucial.


Subject(s)
Gait Disorders, Neurologic/diagnosis , Gait Disorders, Neurologic/therapy , Geriatric Assessment/methods , Nervous System Diseases/diagnosis , Nervous System Diseases/therapy , Aged , Aged, 80 and over , Diagnosis, Differential , Female , Gait Disorders, Neurologic/etiology , Humans , Male , Nervous System Diseases/complications
SELECTION OF CITATIONS
SEARCH DETAIL
...