ABSTRACT
BACKGROUND: Proximal esophageal heterotopic gastric mucosa or so-called inlet patch in the cervical oesophagus is easily missed on endoscopic examination because of its localisation, usually just below the upper oesophageal sphincter. We evaluated the clinical use of narrow band imaging for detection of inlet patches. METHODS: In this prospective, controlled observational study, 1407 subsequent patients underwent oesophagogastroduodenoscopy with or without narrow band imaging on withdrawal of the endoscope in the cervical oesophagus. RESULTS: One endoscopist who was not aware of the prospective observation documented 6 (1.17%) cases of inlet patches in 515 oesophagogastroduodenoscopies compared to 4 cases out of 382 (1.05%) performed by the endoscopist who paid special attention to the presence of inlet patches but did not routinely apply narrow band imaging (OR 0.89, CI 95% 0.25-3.20, p=0.85). In comparison, 17 cases of inlet patches out of 510 (3.33%) were detected by the endoscopist who routinely applied narrow band imaging. The detection rate of proximal oesophageal heterotopic gastric mucosa using narrow band imaging was significantly higher compared to white light endoscopy only (OR 3.06, CI 95% 1.39-6.73, p=0.005). CONCLUSIONS: Withdrawal of the endoscope from the cervical oesophagus using narrow band imaging increased the detection of inlet patches about three-fold compared to standard white light endoscopy.
Subject(s)
Choristoma/diagnosis , Esophageal Diseases/diagnosis , Gastric Mucosa , Narrow Band Imaging , Aged , Endoscopy, Gastrointestinal/methods , Female , Humans , Light , Male , Middle Aged , Neck , Prospective StudiesABSTRACT
A 70-year-old woman with a past medical history of FIGO stage IIIA cervical cancer presented with severe pain in her right leg and after investigations was found to have isolated metastases within the right tibia, fibula and calcanuem. Bone metastases from cervical cancer are relatively rare and tend to occur in the spine and pelvis. There are only a handful of case reports of isolated long bone metastases from cervical cancer in the literature. This case highlights the importance of diagnostic imaging and the role of histological confirmation when there is diagnostic uncertainty.