Subject(s)
Abdominal Abscess , Drainage , Retroperitoneal Space , Suppuration/surgery , Surgical Procedures, Operative , Abdominal Abscess/complications , Abdominal Abscess/diagnostic imaging , Abdominal Abscess/physiopathology , Abdominal Abscess/surgery , Acinetobacter Infections/complications , Acinetobacter Infections/physiopathology , Acinetobacter Infections/surgery , Anti-Bacterial Agents/therapeutic use , Combined Modality Therapy , Humans , Male , Middle Aged , Postoperative Care/methods , Proctitis/complications , Proctitis/physiopathology , Proctitis/surgery , Radiography , Retroperitoneal Space/diagnostic imaging , Retroperitoneal Space/physiopathology , Retroperitoneal Space/surgery , Severity of Illness Index , Suppuration/complications , Suppuration/diagnosis , Suppuration/physiopathology , Surgical Procedures, Operative/adverse effects , Surgical Procedures, Operative/methods , Systemic Inflammatory Response Syndrome/etiology , Systemic Inflammatory Response Syndrome/physiopathology , Systemic Inflammatory Response Syndrome/therapy , Treatment OutcomeABSTRACT
In the article the analysis of the survey with 102 patients with gallstone disease involved, 68 of whom underwent cholecystectomy and 34 were treated conservatively, is made. The content of fecal elastase 1 in stool was estimated for diagnostics of exocrine enzyme insufficiency of pancreas by immune-enzyme analysis. It was stated that 90% of patients possess secondary exocrine insufficiency of pancreas in case of gallstone disease. It is the result of complex metabolic liver abnormalities, portal and mesenterial haemodynamics, dysbiosis of large intestine which are the components of a syndrom of maldigestion and appear during gallstone disease progressing long time before hospitalization. Cholecystectomy doesn't eliminate enzyme insufficiency of pancreas. The effectiveness of using new physiological enzymatic drug Panzytrat in a complex therapy of a syndrom of maldigestion in case of gallstone disease is shown.
