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Ukr Biokhim Zh (1999) ; 77(2): 159-61, 2005.
Article in Russian | MEDLINE | ID: mdl-16335250

ABSTRACT

Data on the study of activity of cysteine proteinases and their inhibitors in larynx neoplastic tissues and control mucosa surrounding them are submitted. It is established that cysteine activity was significantly increased and the content of cysteine inhibitors was decreased in the larynx cancer tissue compared to papilloma tissue and control mucosa. The ratios between cysteine activity and level inhibitors is the informative index of the trual potential proteolytic activity in cancer cells and their invasive capacity.


Subject(s)
Cysteine Endopeptidases/metabolism , Cysteine Proteinase Inhibitors/metabolism , Laryngeal Neoplasms/enzymology , Larynx/enzymology , Papilloma/enzymology , Humans , Laryngeal Neoplasms/pathology , Larynx/pathology , Neoplasm Staging , Papilloma/pathology
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