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Vopr Onkol ; 62(4): 524-8, 2016.
Article in Russian | MEDLINE | ID: mdl-30475542

ABSTRACT

The purpose of this paper is the demonstration and analysis of the effectiveness of spinal cord stimulation in treatment of chronic drug-resistant neuropathy pain in a patient with radiation-induced plexopathy. She underwent radiation therapy for cancer of the right breast in 2000. Ten years later she complained with pain and weakness her right arm. After physical examination and investigation right-side brachial plexopathy was diagnosed. Antidepressant and anticonvulsant had positive effect during one year but then pain appeared again. That is why the patient has been implanted the system of epidural electrostimulation of thickening of the cervical spinal cord. During the post-operative period significant improvement of pain relief was noted. The doses of analgesics were decreased. Spinal cord stimulation efficacy for treatment of chronic pain was repeatedly proved in clinical investigation and meta-analyses. Nevertheless spinal cord stimulation effects on radiation-induced neurological disorders and possible pathophysiological mechanisms are not enough examined. All these facts require further investigation.


Subject(s)
Abnormalities, Radiation-Induced/therapy , Brachial Plexus Neuropathies/therapy , Breast Neoplasms/radiotherapy , Chronic Pain/therapy , Abnormalities, Radiation-Induced/diagnosis , Abnormalities, Radiation-Induced/physiopathology , Brachial Plexus Neuropathies/diagnosis , Brachial Plexus Neuropathies/physiopathology , Breast Neoplasms/complications , Breast Neoplasms/physiopathology , Chronic Pain/diagnosis , Chronic Pain/etiology , Chronic Pain/physiopathology , Female , Humans , Middle Aged , Pain Management , Radiotherapy/adverse effects , Spinal Cord Stimulation
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