Subject(s)
Neurocirculatory Asthenia/drug therapy , Occupational Diseases/drug therapy , Propanolamines/therapeutic use , Adult , Clinical Trials as Topic , Female , Humans , Hypertension/drug therapy , Hypertension/etiology , Male , Middle Aged , Neurocirculatory Asthenia/complications , Propranolol/therapeutic useSubject(s)
Hypertension/epidemiology , Occupational Medicine , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , RiskABSTRACT
A new modification is described of the gas chromatographic method for determining chlorphenoxyisobutyrate in blood plasma of patients. Apart from providing good results, the method shows high sensitivity and insignificant discrepancies in the parallel tests. The time course of changes in blood chlorphenoxyisobutyrate, depending on miscleron doses and treatment regimens over a period of three months, has been shown with reference to examination of 40 patients with chronic ischemic heart disease associated with hyperlipoproteinemia.
Subject(s)
Butyrates/blood , Clofibrate/analogs & derivatives , Clofibrate/administration & dosage , Clofibric Acid/blood , Coronary Disease/blood , Adult , Aged , Chromatography, Gas/methods , Chronic Disease , Dose-Response Relationship, Drug , Female , Humans , Male , Middle Aged , Time FactorsABSTRACT
The efficacy of the drug "essentiale" is discussed on the basis of observation over 34 patients suffering from ischemic heart disease with functional hepatic insufficiency and types IIa and IIb hyperlipoproteinemia. Its normalizing effect on the indices of lipid metabolism the flow of blood in the leg and foot, the vascular tone, and liver function is shwon.