1.
Probl Tuberk Bolezn Legk
; (2): 25-8, 2007.
Article
in Russian
| MEDLINE
| ID: mdl-17419331
ABSTRACT
The percentage of T1 lymphocytes in the presence of the unchanged content of T2 cells were shown to be decreased in the peripheral blood of patients with pulmonary tuberculosis as compared with apparently healthy donors. In addition, the patients were found to have a significantly reduced quantity of CD80-expressing monocytes, the relative quantities of Th1 and Tc1 cells were directly related to the count of CD80+ monocytes. It is suggested that decreased CD80+ cells is a cause of ineffective antigen presentation that results in a systemic reduction in the count of CD4+ and CD8+ cells producing T1 cytokines and in impairment of an effective specific T1 response.
Subject(s)
B7-1 Antigen/immunology , Monocytes/immunology , T-Lymphocytes/immunology , Tuberculosis, Pulmonary/blood , Adolescent , Adult , Blood Donors , CD4 Antigens/immunology , CD8 Antigens/immunology , Humans , Middle Aged , T-Lymphocytes, Helper-Inducer/immunology , T-Lymphocytes, Regulatory/immunology , Tuberculosis, Pulmonary/immunology
2.
Biull Eksp Biol Med
; 127(1): 63-5, 1999 Jan.
Article
in Russian
| MEDLINE
| ID: mdl-10190008
3.
Biull Eksp Biol Med
; 125(6): 660-2, 1998 Jun.
Article
in Russian
| MEDLINE
| ID: mdl-9693761
Subject(s)
B-Lymphocytes/metabolism , Bone Marrow Cells/cytology , Cytotoxicity, Immunologic , Lymphocyte Activation , T-Lymphocytes/metabolism , Animals , B-Lymphocytes/immunology , Bone Marrow Cells/immunology , Cell Division/immunology , Cells, Cultured , Leukemia L1210/immunology , Leukemia L1210/pathology , Mice , Mice, Inbred BALB C , Spleen/cytology , Spleen/immunology , Spleen/metabolism , T-Lymphocytes/immunology , Tumor Cells, Cultured
4.
Biull Eksp Biol Med
; 125(4): 437-9, 1998 Apr.
Article
in Russian
| MEDLINE
| ID: mdl-9631731