ABSTRACT
For afternoon colonoscopy, same-day administration of sodium picosulfate, magnesium oxide, and citric acid (PM/Ca) is recommended. However, few studies have evaluated the bowel-cleansing efficacy and safety of this regimen. The aim of this study was to compare the bowel-cleansing efficacy, side effects, and patient's tolerability of a same-day split administration of PM/Ca with polyethylene glycol (PEG) for afternoon colonoscopy. Patients were randomly assigned to a PM/Ca group or a PEG group. The PM/Ca group consumed 1 sachet of PM/Ca at 06:00 and 1 sachet of PM/Ca 4âhours before the colonoscopy. They also took 2 tablets of bisacodyl before sleep on the night before. The PEG group consumed 2âL of PEG at 06:00 and 2âL of PEG 4âhours before the colonoscopy. All subjects were instructed to finish the bowel cleanser or fluid at least 2âhours before colonoscopy. All colonoscopic examinations were performed in the afternoon on the same day. The bowel-cleansing efficacy was scored using 2 scales: the Ottawa Bowel Preparation Scale (OBPS) and the Aronchick scale. Ease of using the bowel cleanser was rated from 1 (very easy) to 5 (very difficult). Two hundred nine patients underwent colonoscopy. The bowel-cleansing scores by OBPS did not differ between groups (5.0 vs 4.9, Pâ=â0.63). Ease of using the bowel cleanser was superior in the PM/Ca group (Pâ<â0.01). The cleansing efficacy of PM/Ca administered on the day of colonoscopy is comparable to that of PEG. Patients prefer PM/Ca.
Subject(s)
Cathartics/therapeutic use , Colonoscopy/methods , Adult , Bisacodyl/therapeutic use , Cathartics/administration & dosage , Cathartics/adverse effects , Citrates/therapeutic use , Citric Acid/therapeutic use , Female , Humans , Magnesium Oxide/therapeutic use , Male , Middle Aged , Organometallic Compounds/therapeutic use , Picolines/therapeutic use , Polyethylene Glycols/therapeutic use , Prospective Studies , Single-Blind MethodABSTRACT
Several new technologies have been developed to improve the diagnostic capability of conventional endoscopic techniques. One of these most frequently used methods is chromoendoscopy with Lugol's solution in the esophagus to detect malignant lesions. This method has been used for several decades and is generally considered as a safe method, only a few cases of side effects having been reported. We describe a case of acute esophageal and gastric mucosal damage after application of Lugol's solution during endoscopy in an 84-year-old woman. Endoscopists should be aware of the potential for adverse reactions to iodine staining.
