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Fiziol Zh SSSR Im I M Sechenova ; 77(9): 224-31, 1991 Sep.
Article in Russian | MEDLINE | ID: mdl-1666608

ABSTRACT

In rats with experimental hypertension, mesenteric artery revealed a hypersensitivity to noradrenaline whereas aorta did not differ from normal values of this parameter. The sensitivity of femoral artery was lowered. The microarterioles of hypertensive animals manifested a lower sensitivity to noradrenaline as well. This data suggests that arterial vessels manifest a regional heterogeneity of their functional properties in chronic birenal renovascular hypertension.


Subject(s)
Arteries/physiopathology , Hypertension, Renovascular/physiopathology , Animals , Aorta/drug effects , Aorta/physiopathology , Arteries/drug effects , Chronic Disease , Dose-Response Relationship, Drug , Femoral Artery/drug effects , Femoral Artery/physiopathology , Male , Mesenteric Arteries/drug effects , Mesenteric Arteries/physiopathology , Microcirculation/drug effects , Microcirculation/physiopathology , Norepinephrine/pharmacology , Rats , Rats, Inbred Strains
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