[Age-related changes in mosquito insecticide resistance and their relation to the mechanisms of detoxication]. / Vozrastnye izmeneniia rezistentnosti komarov k insektitsidam i ikh sviaz' s mekhanizmami detoksikatsii.

The mechanisms of DDT, permethrin and malathion resistance were determined indirectly by means of synergists inhibiting the detoxification enzymes. It was found that metabolic resistance dependent on glutathione-S-transferase, MFO and carboxylesterase is the most liable to age changes. Such changes are less expressive in mosquitos which have supposedly kdr-resistance. In young mosquitos (1-2 days) of all species, the rate of synergism is relatively low and fails to explain high resistance which is usual for juvenile specimen.

[The sensitivity of a natural population of Anopheles martinius to malathion and DDT in the Kirghiz SSR]. / Chuvstvitel'nost' prirodnoi populiatsii Anopheles martinius k malationu i DDT v Kirgizskoi SSR.

Levels of An. martinius natural population resistance to DDT and malathion were determined in the Kirghiz SSR by a generally accepted WHO method. 100% sensitivity of mosquitoes to malathion and limited DDT-resistance (mean death rate, 59.1%) were revealed. Age-related differences in DDT-resistance level were established. Mosquitoes at the day of imago hatching were less sensitive: the death rate in case of the contact was 42.7%. Blood sucking produced no effect on their resistance.

[The level and nature of insecticide resistance (DDT and malathion) in laboratory-strain mosquitoes]. / Uroven' i priroda rezistentnosti k insektitsidam (DDT i malationu) komarov laboratornykh linii.

Authors characterize 7 mosquito strains and species from the collection of the E. I. Martsinovskii Inst. with regard to the levels and mechanisms of their resistance to malathion and DDT. Resistance mechanisms of the strains An. stephensi, An. sacharovi, An. atroparvus, Ae. aegypti and C. pipiens were determined with the help of synergists. Malathion-resistance in one of the An. stephensi strains is due to high carboxyl activity. Other strains featured various levels of DDT-resistance due to various mechanisms: in Ae. aegypti it was due to mixed-function oxidases activity; in An. atroparvus, An. sacharovi and An. stephensi second strain to glutathione-dependent transferase, in C. pipiens, An stephensi third strain and, partially, An. sacharovi,--to the probable presence of kdr-factor.

[Age-related changes in the sensitivity of mosquito species to DDT]. / Vozrastnye izmeneniia chuvstvitel'nosti komarov raznykh bidov k DDT.

The effect of age on the level of resistance to DDT was studied on laboratory mosquito strains of An. sacharovi, An. atroparvus, Ae. aegypti, C. p. molestus. The highest resistance level was observed in juvenile mosquitos 0-1 days after flying out. The trend towards the increase in sensitivity with age common for all mosquito species is revealed.