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Am J Med Genet ; 59(1): 36-7, 1995 Oct 23.
Article in English | MEDLINE | ID: mdl-8849007

ABSTRACT

We report on the prenatal diagnosis of a baby with a de novo centromeric fission of chromosome 21. Both fission products were mitotically stable. Follow-up chromosome analysis after birth confirmed the centromere fission. This chromosome fission appears to be without clinical significance for this patient.


Subject(s)
Chromosome Aberrations , Chromosomes, Human, Pair 21 , Centromere , Female , Humans , Infant, Newborn , Karyotyping , Pregnancy , Prenatal Diagnosis
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