ABSTRACT
A series of paediatric patients is presented in whom topical interferon alpha-2b was used as a co-adjuvant treatment for conjunctival papilloma. This condition is frequently associated with human papillomavirus infection. There is little information on the pediatric population with the use of interferon for the treatment of these lesions. In this case series, adjuvant treatment with topical interferon alpha-2b in paediatric patients showed no recurrence and good tolerance.
Subject(s)
Chemotherapy, Adjuvant , Conjunctival Neoplasms/drug therapy , Interferon alpha-2/therapeutic use , Neoplasm Recurrence, Local/epidemiology , Papillomavirus Infections/drug therapy , Child , Child, Preschool , Combined Modality Therapy , Conjunctival Neoplasms/surgery , Conjunctival Neoplasms/virology , Cryosurgery , Female , Human papillomavirus 11/isolation & purification , Humans , Interferon alpha-2/administration & dosage , Male , Neoplasm Recurrence, Local/prevention & control , Neoplasm Recurrence, Local/virology , Papillomavirus Infections/surgery , Papillomavirus Infections/virologyABSTRACT
PURPOSE: The aim of this paper is to present the case report of a patient developing endophthalmitis after penetrating keratoplasty caused by a multidrug-resistant Pseudomonas aeruginosa, detected only in the contralateral donor tissue. CASE REPORT: A 77-year-old man underwent an uneventful penetrating keratoplasty with a preoperative culture-negative donor cornea; however, the fellow cornea grew multidrug-resistant Pseudomonas aeruginosa. The patient developed and was treated for endophthalmitis after penetrating keratoplasty, and aqueous and vitreous taps grew P. aeruginosa with antibiotic resistance identical to the isolate from the mate cornea. Sequence analysis of the 16S ribosomal gene from the two isolates and confirmation analyzing the sequence of P. aeruginosa heat shock protein gene (groES) were performed showing the same strain for both organisms. CONCLUSION: This case report documents the presence of the same multidrug-resistant P. aeruginosa causing endophthalmitis after penetrating keratoplasty and in the contralateral donor tissue, suggesting that we must be cautious in deciding to transplant tissues with positive culture in the contralateral donor cornea.
Subject(s)
Corneal Transplantation/adverse effects , Endophthalmitis/microbiology , Postoperative Complications/microbiology , Pseudomonas Infections/etiology , Pseudomonas aeruginosa/immunology , Aged , Cornea/microbiology , Drug Resistance, Microbial/immunology , Humans , Male , Tissue Donors , Transplants/microbiology , Vitreous Body/microbiologySubject(s)
HIV Infections/etiology , Health Personnel , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Needlestick Injuries/drug therapy , Anti-Retroviral Agents/therapeutic use , HIV Infections/prevention & control , Humans , Occupational Exposure/adverse effects , Ophthalmology , Post-Exposure Prophylaxis , Treatment OutcomeABSTRACT
BACKGROUND: Sclerodermatomyositis is an overlap syndrome of myositis and scleroderma, with dermatological, muscular and joint involvement, but may also present with ocular manifestations. CLINICAL CASE: A 57 year-old woman presented with ophthalmological manifestations, including scleral thinning 360°, and the presence of cells in the anterior and posterior chamber. Oriented physical examination and laboratory studies led to the diagnosis, with the need for systemic treatment. CONCLUSION: Sclerodermatomyositis is a rare disease. Its diagnosis needs thorough clinical and laboratory studies, and its management should be multidisciplinary when inflammatory ocular manifestations may be present.
Subject(s)
Eye Diseases/etiology , Myositis/complications , Scleroderma, Systemic/complications , Female , Humans , Middle AgedABSTRACT
OBJECTIVE AND METHODS: A retrospective analysis was performed using the medical records in a referral center in Mexico over a period of 5 years, in order to determine the frequency of acute follicular conjunctivitis. RESULTS AND CONCLUSIONS: A total of 859,986 ophthalmology consultations were given, from which 8,930 were diagnosed with acute follicular conjunctivitis (1.03% of the total). The number of patients diagnosed range between 100 and 200 in the majority of months. In August 2012 an increase was observed with 308 cases, and then decreasing after two months. This study did not demonstrate a highest frequency by month, with exception of year 2012 that showed a peak incidence in the third trimester.
