[Neurogenic lesions of the lungs in severe craniocerebral trauma]. / Neirogennye porazheniia legkikh pri tiazheloi cherepno-mozgovoi travme.

The role of sympathicotonia in the development of neurogenic edema of the lungs in patients with the craniocerebral trauma (CCT) was confirmed experimentally. Morphological examinations of the lungs in 12 people who died from CCT have revealed the stage-wise character of the development of neurodystrophic alterations in the air-conducting and respiratory parts, up to the development of denervation.

[Trauma to the cranial nerve roots in the pathogenesis of brain stem lesions in severe craniocerebral injury]. / Travmatizatsiia koreshkov cherepnykh nervov v patogeneze stvolovykh porazhenii pri tiazheloi cherepno-mozgovoi travme.

A clinico-morphological analysis of results of 65 autopsies has shown that traumatization of cranial nerve roots at the moment of trauma is one of pathogenetical mechanisms of truncal lesions. A group of primary progressing truncal lesions was established which included 81.1% of patients who died at the hospital.

[The selective spatial filtration of roentgenograms in the forensic medical expertise of stab-cutting wounds]. / Selektivnaia prostranstvennaia fil'tratsiia rentgenogramm pri sudebno-meditsinskoi ékspertize koloto-rezanykh ran.

Investigation of 14 roentgenograms of skin preparations with cut-stab wounds, treated by spatial filtration method in medium and high spatial frequency modes was performed using material of 13 specific cases. This resulted in detection of disturbances of skin pattern left at the area of former skin cone in 7 cases while in 2 cases indistinct heel traces were seen. Changes in skin pattern were not recorded on roentgenograms of skin preparation of 12 experimental cut-stab wounds obtained on cadaveric skin.

[The differential diagnosis and the identification importance of the track of the heel of stabbing-cutting weapons in skin wounds]. / Differentsial'naia diagnostika i identifikatsionnoe znachenie sleda piatki koliushche-rezhushchikh orudii v ranakh kozhi.

Data on 123 cut-stab wounds and 52 knives were examined in the course of medicolegal expert evaluation. It was found that 30 knives possessed heels which could have two forms: symmetric and asymmetric. Heel traces were seen in 16 expert evaluations (34%) in 31 wounds (25.2%) and in some of them particular features of knife blade heel were represented. Differences between butt end and heel trace according to series of signs were noted.

[Pulmonary complications in severe cranio-cerebral injury]. / Legochnye oslozhneniia pri tiazheloi cherepno-mozgovoi travme.

An analysis of 2049 autopsies and experimental investigations in 150 albino rats have shown that pulmonary complications developing during the first two weeks after cranio-cerebral traumas include pulmonary edema, aspiration syndrome, pneumonia. The pulmonary injuries are based on several pathogenetic mechanisms associated with the effect of hemodynamics, humoral factors, activation of leukocytes, aspiration and infection. Disturbed hemodynamics and vascular permeability in the lungs can be due to functional alterations in the zone of vascular-motor and respiratory centers.

[Protective action of thyroliberin and its synthetic analog (PR-546) in craniocerebral trauma]. / Protektornoe deistvie tiroliberina i ego sinteticheskogo analoga (PR-546) pri cherepno-mozgovoi travme.

The effect of TRH and its synthetic analogue (PR-546) devoid of hormonal activity was studied in acute experiments on rats on the model of neurogenic lung edema caused by skull injury. It was proved that the preliminary (for 30 min before the injury) i/p introduction of TRH (in doses 0.5-1 mg/kg) and PR-546 (in doses 4-8 mg/kg) prevented the development of acute edema and the changes of blood gas compositions as well as disorders in breathing after skull injury. It was assumed that the protective effect of studied peptides is possibly achieved through the intensification of breathing and cardiovascular centers activity.

[The macro- and micromorphological signs of the edge of stabbing-cutting weapons in skin wounds]. / Makro- i mikromorfologicheskie priznaki ostriia koliushche-rezhushchikh orudii v ranakh kozhi.

110 stab-cut skin wounds in 34 dead bodies as well as 38 stab-cut instruments were studied. Three morphologic types of traces left by blade edges of stab-cut instruments, i.e. puncture, microrupture and microcut, were established. Gross and micromorphology of each of these traces depends on the properties of blade edges of stab-cut instruments.