ABSTRACT
ABSTRACT: Prostate-specific membrane antigen (PSMA) PET/CT has revolutionized the imaging of prostate cancer. Historically, prostate cancer metastasis to thyroid and cricoid cartilages was thought to be exceedingly rare, with only a few reported cases in the literature. Prostate cancer metastasis to the laryngeal cartilages was detected in 4 of 221 patients who underwent imaging with 18 F-PSMA (Pylarify) or 68 Ga-PSMA (Illuccix) PET/CT for initial staging of high-risk prostate cancer or restaging evaluation in the setting of biochemical recurrence from April 2022 through October 2023. The increased sensitivity and specificity of PSMA PET/CT allow for the detection of previously occult metastatic disease.
Subject(s)
Genital Neoplasms, Female , Prostatic Neoplasms , Male , Female , Humans , Positron Emission Tomography Computed Tomography/methods , Prostate/pathology , Thyroid Gland/pathology , Cricoid Cartilage/diagnostic imaging , Cricoid Cartilage/pathology , Prostatic Neoplasms/diagnostic imaging , Prostatic Neoplasms/pathology , Gallium Radioisotopes , Genital Neoplasms, Female/pathology , Prostate-Specific AntigenABSTRACT
Many challenges exist for the rural patient in need of joint arthroplasty. Optimization for surgery is more difficult due to factors such as deprivation, education, employment, household income, and access to proper surgical institutions. Rural individuals have less access to primary care and even less access to surgical specialists, creating a distinct subset of patients who endure higher costs, poorer outcomes, and lack of care. Reducing socioeconomic disparities in rural communities will require policy initiatives addressing the components of socioeconomic status (income, education, and occupation). Hopefully remote patient technologies can help with access and timely addressing of modifiable risk factors.
