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2.
Int J Neural Syst ; 21(4): 265-76, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21809474

ABSTRACT

While feedforward neural networks have been widely accepted as effective tools for solving classification problems, the issue of finding the best network architecture remains unresolved, particularly so in real-world problem settings. We address this issue in the context of credit card screening, where it is important to not only find a neural network with good predictive performance but also one that facilitates a clear explanation of how it produces its predictions. We show that minimal neural networks with as few as one hidden unit provide good predictive accuracy, while having the added advantage of making it easier to generate concise and comprehensible classification rules for the user. To further reduce model size, a novel approach is suggested in which network connections from the input units to this hidden unit are removed by a very straightaway pruning procedure. In terms of predictive accuracy, both the minimized neural networks and the rule sets generated from them are shown to compare favorably with other neural network based classifiers. The rules generated from the minimized neural networks are concise and thus easier to validate in a real-life setting.


Subject(s)
Algorithms , Artificial Intelligence , Neural Networks, Computer , Decision Making , Models, Statistical
3.
Neural Netw ; 21(7): 1020-8, 2008 Sep.
Article in English | MEDLINE | ID: mdl-18442894

ABSTRACT

This paper proposes a GRG (Greedy Rule Generation) algorithm, a new method for generating classification rules from a data set with discrete attributes. The algorithm is "greedy" in the sense that at every iteration, it searches for the best rule to generate. The criteria for the best rule include the number of samples and the size of subspaces that it covers, as well as the number of attributes in the rule. This method is employed for extracting rules from neural networks that have been trained and pruned for solving classification problems. The classification rules are extracted from the neural networks using the standard decompositional approach. Neural networks with one hidden layer are trained and the proposed GRG algorithm is applied to their discretized hidden unit activation values. Our experimental results show that neural network rule extraction with the GRG method produces rule sets that are accurate and concise. Application of GRG directly on three medical data sets with discrete attributes also demonstrates its effectiveness for rule generation.


Subject(s)
Algorithms , Artificial Intelligence , Data Interpretation, Statistical , Neural Networks, Computer , Flowers/classification , Humans , Neoplasms/classification , Reproducibility of Results , Software
4.
IEEE Trans Syst Man Cybern B Cybern ; 38(2): 299-309, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18348915

ABSTRACT

Various benchmarking studies have shown that artificial neural networks and support vector machines often have superior performance when compared to more traditional machine learning techniques. The main resistance against these newer techniques is based on their lack of interpretability: it is difficult for the human analyst to understand the reasoning behind these models' decisions. Various rule extraction (RE) techniques have been proposed to overcome this opacity restriction. These techniques are able to represent the behavior of the complex model with a set of easily understandable rules. However, most of the existing RE techniques can only be applied under limited circumstances, e.g., they assume that all inputs are categorical or can only be applied if the black-box model is a neural network. In this paper, we present Minerva, which is a new algorithm for RE. The main advantage of Minerva is its ability to extract a set of rules from any type of black-box model. Experiments show that the extracted models perform well in comparison with various other rule and decision tree learners.


Subject(s)
Algorithms , Artificial Intelligence , Decision Support Techniques , Information Storage and Retrieval/methods , Pattern Recognition, Automated/methods
5.
Genomics Proteomics Bioinformatics ; 3(2): 84-93, 2005 May.
Article in English | MEDLINE | ID: mdl-16393145

ABSTRACT

Microarray technology can be employed to quantitatively measure the expression of thousands of genes in a single experiment. It has become one of the main tools for global gene expression analysis in molecular biology research in recent years. The large amount of expression data generated by this technology makes the study of certain complex biological problems possible, and machine learning methods are expected to play a crucial role in the analysis process. In this paper, we present our results from integrating the self-organizing map (SOM) and the support vector machine (SVM) for the analysis of the various functions of zebrafish genes based on their expression. The most distinctive characteristic of our zebrafish gene expression is that the number of samples of different classes is imbalanced. We discuss how SOM can be used as a data-filtering tool to improve the classification performance of the SVM on this data set.


Subject(s)
Computational Biology/methods , Gene Expression Profiling/methods , Gene Expression Regulation/genetics , Zebrafish/genetics , Animals , Multigene Family/genetics , Zebrafish/classification
6.
Comput Biol Med ; 32(4): 237-46, 2002 Jul.
Article in English | MEDLINE | ID: mdl-11931862

ABSTRACT

We present our results from combining the predictions of an ensemble of neural networks for the diagnosis of hepatobiliary disorders. To improve the accuracy of the diagnosis, we train the second level networks using the outputs of the first level networks as input data. The second level networks achieve an accuracy that is higher than that of the individual networks in the first level. Compared to the simple method which averages the outputs of the first level networks, the second level networks are also more accurate. We discuss how the overall predictive accuracy can be improved by introducing bias during the training of the level one networks.


Subject(s)
Carcinoma, Hepatocellular/diagnosis , Cholelithiasis/diagnosis , Diagnosis, Computer-Assisted , Liver Cirrhosis/diagnosis , Liver Diseases, Alcoholic/diagnosis , Liver Neoplasms/diagnosis , Neural Networks, Computer , Bias , Diagnosis, Differential , Humans , Liver Function Tests
7.
Neural Netw ; 12(1): 191-192, 1999 Jan.
Article in English | MEDLINE | ID: mdl-12662727

ABSTRACT

We write this letter to comment on the "virtual input" phenomenon reported by Thaler (Neural Networks, 8(1) (1995) 55-65). The author attributed the phenomenon to the network's ability to perform pattern classification and completion, and reported that pruning probability affects the number of virtual inputs observed. Our independent study of Thaler's results, however, reveals a simpler explanation of the "virtual input" phenomenon.

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