Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 74
Filter
1.
Clin Orthop Surg ; 16(3): 390-396, 2024 Jun.
Article in English | MEDLINE | ID: mdl-38827754

ABSTRACT

Background: The purpose of this study was to evaluate functional outcomes, radiologic results, and complications after hybrid total hip arthroplasty (THA) in patients with subchondral insufficiency fractures (SIFs) of the femoral head. Methods: From June 2009 to December 2020, among 985 patients who underwent hybrid THA at our hospital, 19 patients diagnosed with SIF through a retrospective chart review were included. Those under 50 years of age, with radiographic findings of osteonecrosis on the contralateral side of surgery, a history of organ transplantation, and alcohol abuse, were excluded. Functional evaluation was performed using a modified Harris Hip Score (HHS). After surgery, inclination and anteversion of the acetabular cup and version of the femoral system were measured using postoperative x-ray. The outpatient follow-up was performed at 6 weeks, 3 months, 9 months, and 12 months after surgery and every year thereafter. Complications including dislocation, implant loosening, stem subsidence, and periprosthetic infection were observed on follow-up radiographs. Results: The average follow-up time was 29.3 ± 9.1 months (range, 24-64 months) with no loss to follow-up. The mean modified HHS was 83.4 ± 9.6 (range, 65-100) at the last outpatient clinic follow-up. The average inclination of the acetabular cup was 41.9° ± 3.4° (range, 37°-48°), and the anteversion was 27.5° ± 6.7° (range, 18°-39°). The version of the femoral stem was 19° ± 5.7° (range, 12°-29°). There was no case of intraoperative fracture. There were no cases of dislocation, loosening of the cup, subsidence of the femoral stem, intraoperative or periprosthetic fracture, or periprosthetic infection on the follow-up radiographs. Conclusions: In our study, hybrid THA showed favorable outcomes in patients diagnosed with SIF, and there were no further special considerations as for THA performed due to other diseases or fractures.


Subject(s)
Arthroplasty, Replacement, Hip , Fractures, Stress , Humans , Arthroplasty, Replacement, Hip/adverse effects , Middle Aged , Male , Female , Retrospective Studies , Fractures, Stress/surgery , Fractures, Stress/diagnostic imaging , Fractures, Stress/etiology , Adult , Femur Head/surgery , Femur Head/diagnostic imaging , Femur Head/injuries , Aged , Hip Fractures/surgery , Hip Fractures/diagnostic imaging , Postoperative Complications
2.
Article in English | WPRIM (Western Pacific) | ID: wpr-1042748

ABSTRACT

Background@#The purpose of this study was to evaluate functional outcomes, radiologic results, and complications after hybrid total hip arthroplasty (THA) in patients with subchondral insufficiency fractures (SIFs) of the femoral head. @*Methods@#From June 2009 to December 2020, among 985 patients who underwent hybrid THA at our hospital, 19 patients diagnosed with SIF through a retrospective chart review were included. Those under 50 years of age, with radiographic findings of osteonecrosis on the contralateral side of surgery, a history of organ transplantation, and alcohol abuse, were excluded. Functional evaluation was performed using a modified Harris Hip Score (HHS). After surgery, inclination and anteversion of the acetabular cup and version of the femoral system were measured using postoperative x-ray. The outpatient follow-up was performed at 6 weeks, 3 months, 9 months, and 12 months after surgery and every year thereafter. Complications including dislocation, implant loosening, stem subsidence, and periprosthetic infection were observed on follow-up radiographs. @*Results@#The average follow-up time was 29.3 ± 9.1 months (range, 24–64 months) with no loss to follow-up. The mean modified HHS was 83.4 ± 9.6 (range, 65–100) at the last outpatient clinic follow-up. The average inclination of the acetabular cup was 41.9° ± 3.4° (range, 37°–48°), and the anteversion was 27.5° ± 6.7° (range, 18°–39°). The version of the femoral stem was 19° ± 5.7° (range, 12°–29°). There was no case of intraoperative fracture. There were no cases of dislocation, loosening of the cup, subsidence of the femoral stem, intraoperative or periprosthetic fracture, or periprosthetic infection on the follow-up radiographs. @*Conclusions@#In our study, hybrid THA showed favorable outcomes in patients diagnosed with SIF, and there were no further special considerations as for THA performed due to other diseases or fractures.Keywords

3.
Article in English | WPRIM (Western Pacific) | ID: wpr-966707

ABSTRACT

Background@#Scapular surgery is usually undertaken via the posterior approach described by Judet. This approach allows access to the entire posterior scapular body; however, it results in severe soft-tissue injury and requires an incision in the deltoid muscle.To date, no clinical study has been reported on open reduction and internal fixation without capsular incision for displaced inferior glenoid fractures (Ideberg type II). The purpose of this study was to introduce an easy and less invasive approach to the inferior glenoid fossa and evaluate its clinical outcomes. @*Methods@#Ten patients with displaced inferior glenoid fractures underwent open reduction and internal fixation without capsular incision between January 2017 and July 2018. Postoperative computed tomography was performed to evaluate the reduction state within a week of the surgery. Clinical and radiological data from 7 patients who were followed up for more than 2 years were analyzed. @*Results@#The mean age of the patients was 61.7 years (range, 35–87 years). The mean follow-up period was 28.6 months (range, 24–42 months). The mean preoperative fracture gap and step-off values were 12.3 ± 4.4 mm and 6.8 ± 4.0 mm, respectively. Surgical stabilization was conducted 6.4 days (range, 4–13 days) after trauma. Mean postoperative-preoperative fracture gap and stepoff values were 0.6 ± 0.6 mm and 0.6 ± 0.8 mm, respectively. At 24 months after surgery, the mean Constant score was 89.1 ± 10.6 points (range, 69–100) and the mean pain visual analog scale score was 1.4 ± 1.7 (range, 0–5). Bony union was observed in all patients. The mean time to bony union was 11 ± 1.7 weeks. The mean active range values for forward elevation, external rotation, and abduction were 162.9° ± 11.1° (range, 150°–180°), 55.7° ± 15.1° (range, 30°–70°), and 158.6° ± 10.7° (range, 150°–180°), respectively. @*Conclusions@#The presented posterior open reduction and internal fixation without capsular incision or extensive soft-tissue dissection may be an easy and less invasive surgical approach for inferior glenoid fossa fractures (Ideberg type II).

4.
Integr Med Res ; 10(3): 100706, 2021 Sep.
Article in English | MEDLINE | ID: mdl-33665094

ABSTRACT

BACKGROUND: This study aimed to obtain the symptom, prescription and therapeutic patterns for the treatment of patients with menopausal syndrome in major Korean medicine (KM) hospitals. METHODS: We used a retrospective chart review of climacteric disorder and postmenopausal syndrome patients by examining medical records (ICD-10, menopausal and female climacteric states: N95.1, Menopausal and perimenopausal disorder, unspecified: N95.9) from eight university KM hospitals in South Korea. RESULTS: The main symptoms of 1,682 patients with menopausal disorders visiting eight college-affiliated oriental medicine hospitals were hot flush, hyperhidrosis, fatigue, insomnia, and chest tightness. Guipi decoction, Si-wu guipi decoction, Qing-xin lianzi-yin, Jiawei xiao-yao-san and Guipi wen-dan decoction were the most commonly prescribed treatments for menopausal disorders. Patients were most often treated with a combination of herbal medicine and acupuncture. CONCLUSION: Our study shows that the current prescribed herbal medicines were used for treating menopausal disorders in Korean medicine hospitals. However, the objectivity of the efficacy assessment should be studied further.

5.
Gut and Liver ; : 217-224, 2021.
Article in English | WPRIM (Western Pacific) | ID: wpr-874596

ABSTRACT

Background/Aims@#Chitosan, a natural polymer widely used in the biomaterials field, has been proposed as a potential submucosal injection solution. The purpose of this study was to compare the performance and efficacy of aqueous chitosan solution and commercialized submucosal injection fluids using a three-dimensional sensor and to evaluate the efficacy of the measured parameters. @*Methods@#Normal saline (0.9% NaCl), as a control, Eleview ® (Poloxamer 188), Blue Eye TM (0.4% hyaluronic acid), and aqueous chitosan solution (2.0%) were injected into the submucosa of porcine stomachs ex vivo. The mucosal elevation height, elevated surface area, and angle of the tangent of the submucosal fluid cushion were measured using a three-dimensional sensor. The rates of change for each variable were calculated, and the correlation between parameters was analyzed. Tissue specimens were stained with hematoxylin and eosin. @*Results@#All variables exhibited the highest values under chitosan injection. The mucosal elevation height rate of change differed significantly between normal saline and chitosan solution (p=0.024). The elevated surface area rates of change for normal saline and Eleview® were significantly different from those for TS-905 and chitosan solution (p=0.006 and p=0.009, respectively). Further, height, area, and angle showed a positive correlation (p<0.001). A histological examination revealed an even distribution of aqueous chitosan within the submucosa without tissue damage. @*Conclusions@#Aqueous chitosan was superior to normal saline and Eleview® and was noninferior to TS-905. A three-dimensional sensor and the measured parameters were effective and useful for evaluating the performance of submucosal fluids.

6.
Article | WPRIM (Western Pacific) | ID: wpr-836377

ABSTRACT

Bisphosphonates can cause atypical fractures when taken for a long time. Atypical fractures appear mainly as femoral subtrochanteric or shaft fractures. On the other hand, reports of atypical fractures in the proximal ulna are relatively rare, with a high proportion of nonunion cases. This paper reports a case of nonunion after fixation for atypical fractures of the proximal ulna.

7.
Article | WPRIM (Western Pacific) | ID: wpr-836378

ABSTRACT

Femoral head fractures combined with hip dislocation are very rare injuries. In most cases, they result from high-energy trauma to the hip or lower extremity during traffic accidents. Various therapy options have been suggested to treat these injuries. Especially, different joint-preserving surgical options have been described for the treatment of traumatic osteochondral injury of the femoral head in young, active patients. In this report, we present a case that a traumatic osteochondral lesion to the femoral head after hip dislocation was treated with osteochondral autografts (OATS) from the non-weight-bearing area of the ipsilateral inferior femoral head through a surgical hip dislocation. After 1 year, the clinical and radiological outcome was satisfactory with no evidence of posttraumatic osteoarthritis and no pain of patients.

8.
Article in English | WPRIM (Western Pacific) | ID: wpr-914128

ABSTRACT

BACKGROUND@#This study investigates the effects of neuromuscular electrical stimulation (NMES) in preventing deltoid atrophy during the first 12 weeks after arthroscopic rotator cuff repair.@*METHODS@#Eighteen patients undergoing arthroscopic repair of a medium-sized rotator cuff tear by a single surgeon, were randomized into two groups: NMES and transcutaneous electrical nerve stimulation (TENS). Each group used the respective device for 6 weeks after surgery. Pain was measured at baseline, 6, and 12 weeks postoperatively, using the visual analogue scale (VAS); range of motion (ROM), abduction strength and functional scores were measured at baseline and 12 weeks postoperatively. Deltoid thickness and cross-sectional areas were measured using magnetic resonance imaging at 12 weeks postoperatively.@*RESULTS@#At 12 weeks post-surgery, no statistically significant difference was observed between the NMES and TENS groups in the pain VAS, the Disabilities of the Arm, Shoulder and Hand score, ROM, and abduction strength. Postoperative decrease in the thickness of the anterior, middle, and posterior deltoid, at the level just below the coracoid, was −2.5%, −0.7%, and −6.8%, respectively, in the NMES group, and −14.0%, −2.6%, and −8.2%, respectively, in the TENS group (p=0.016, p=0.677, and p=0.791, respectively). At the level of the inferior glenoid tubercle, postoperative decrease in area of the deltoid was −5.4% in the NMES group and −14.0% in the TENS group, which was significantly different (p=0.045).@*CONCLUSIONS@#NMES has the potential for reducing deltoid atrophy after arthroscopic rotator cuff repair, suggesting that NMES might help minimize postoperative atrophy after various shoulder surgeries.

9.
Article in English | WPRIM (Western Pacific) | ID: wpr-760271

ABSTRACT

OBJECTIVE: To compare inferior capsular redundancy by using magnetic resonance arthrography (MRA) images in patients with multidirectional instability (MDI) of the shoulder and control subjects without instability and thereby develop a screening method to identify the presence of shoulder MDI. MATERIALS AND METHODS: The MRA images of patients with MDI of the shoulder (n = 65, 57 men, 8 women; mean age, 24.5 years; age range, 18–42 years) treated over an eight-year period were retrospectively reviewed; a control group (n = 65, 57 men, 8 women; mean age, 27.4 years; age range, 18–45 years) without instability was also selected. The inferior capsular redundancy was measured using a new method we named the glenocapsular (GC) ratio method. MRA images of both groups were randomly mixed together, and two orthopedic surgeon reviewers measured the cross-sectional areas (CSAs) and sagittal capsule-head ratios on oblique sagittal images, as well as the axial capsule-head ratios on axial images and GC ratios on oblique coronal images. RESULTS: The CSAs and GC ratios were significantly higher in patients than in controls (both, p 1.42 was found to be most suggestive of MDI of the shoulder, owing to its high sensitivity (92.3%) and specificity (89.2%). CONCLUSION: GC ratio can be easily measured and used to accurately screen for MDI of the shoulder.


Subject(s)
Female , Humans , Male , Arthrography , Mass Screening , Methods , Orthopedics , Retrospective Studies , Sensitivity and Specificity , Shoulder
10.
Pharmaceutics ; 10(4)2018 Dec 01.
Article in English | MEDLINE | ID: mdl-30513750

ABSTRACT

The objective of this study was to characterize pharmacokinetics (PKs) of kaurenoic acid (KAU) after administration of the clinical usual dose of Araliae Continentalis Radix extract powder to Korean subjects for the first time and evaluate the mechanism of its absorption in vitro. A simple, sensitive, and selective analytical method was developed for the detection of KAU in human plasma. Concentrations of KAU were quantified by ultra-performance liquid chromatography tandem mass spectrometry after simple liquid⁻liquid extraction. This pharmacokinetic model of KAU was best described by a two-compartment model with first-order absorption. To identify efflux transporters involved in the absorption of KAU, a Caco-2 monolayer model was used. Estimated PK parameters were: systemic clearance, 23.89 L/h; inter-compartmental clearance, 15.55 L/h; rate constant for absorption, 1.72 h-1; volume of distribution of the central compartment, 24.44 L; and volume of distribution of the peripheral compartment, 64.05 L. Results from Caco-2 bidirectional transport study suggested that KAU was a potential substrate of efflux transporters. In summary, PKs of KAU were successfully characterized after administration of a usual dose of Araliae continentalis Radix extract powder in human with the newly developed bioanalytical method and the mechanism of absorption of KAU was identified clearly.

11.
Article in English | MEDLINE | ID: mdl-30081350

ABSTRACT

The purpose of this study was to develop a method for simultaneous analysis of schizandrin, ephedrine, paeoniflorin, and cinnamic acid as constituents of Socheongryong-tang tablet in human plasma using UPLC-MS/MS. These four components were separated using water containing 0.01% formic acid and methanol as a mobile phase by gradient elution at a flow rate of 0.3 mL/min with a HALO-C18 column (2.1 mm × 100 mm, 2.7 µm particle size). Quantitation was performed on a triple quadrupole mass spectrometer employing electrospray ionization technique operated in multiple reaction monitoring mode. Mass transitions were m/z 432.9 → 384.1 for schizandrin, 165.8 → 148.1 for ephedrine, 525.0 → 449.2 for paeoniflorin, 146.8 → 102.9 for cinnamic acid, and 340.0 → 324.0 for papaverine as internal standard. Liquid-liquid extraction and protein precipitation with ethyl acetate-methanol (1:2, v/v) were used to obtain these four components. Chromatograms showed high resolution, sensitivity, and selectivity without interference by plasma constituents. Calibration curves of schizandrin, ephedrine, paeoniflorin, and cinnamic acid in human plasma ranged from 0.02 to 8 ng/mL, 0.5 to 200 ng/mL, 0.2 to 80 ng/mL, and 1 to 400 ng/mL, respectively. Calibration curves of each analyte displayed excellent linearity, with correlation coefficients > 0.99. For all four components, both intra- and inter-day precisions (CV%) were <5.99%. The accuracy was 99.35-103.30% for schizandrin, 98.48-104.38% for ephedrine, 97.06-103.34% for paeoniflorin, and 99.97-104.36% for cinnamic acid. This analytical method developed in this study satisfied the criteria of international guidance. It could be successfully applied to pharmacokinetic studies of schizandrin, ephedrine, paeoniflorin, and cinnamic acid after oral administration of Socheongryong-tang tablet to humans.


Subject(s)
Cinnamates/blood , Cyclooctanes/blood , Drugs, Chinese Herbal/chemistry , Drugs, Chinese Herbal/pharmacokinetics , Ephedrine/blood , Glucosides/blood , Lignans/blood , Monoterpenes/blood , Polycyclic Compounds/blood , Administration, Oral , Adult , Chromatography, High Pressure Liquid/methods , Cinnamates/chemistry , Cinnamates/pharmacokinetics , Cyclooctanes/chemistry , Cyclooctanes/pharmacokinetics , Drugs, Chinese Herbal/administration & dosage , Ephedrine/chemistry , Ephedrine/pharmacokinetics , Glucosides/chemistry , Glucosides/pharmacokinetics , Humans , Lignans/chemistry , Lignans/pharmacokinetics , Linear Models , Male , Middle Aged , Monoterpenes/chemistry , Monoterpenes/pharmacokinetics , Polycyclic Compounds/chemistry , Polycyclic Compounds/pharmacokinetics , Reproducibility of Results , Sensitivity and Specificity , Tandem Mass Spectrometry/methods , Young Adult
12.
J Pharmacopuncture ; 21(4): 258-267, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30652052

ABSTRACT

OBJECTIVES: The purpose of this study was to find out validity of Surface Electromyography(sEMG) compared with Nerve Conduction Study and clinical assessment scale as assessment factors for facial palsy. METHODS: We investigated 50 cases of patients with peripheral facial palsy who had records of sEMG and NCS to check. Then we analyzed the correlation between sEMG and NCS that carried out around 1 week after onset. And we analyzed the correlation between sEMG and clinical assessment scales that were measured three times around 1 week, 3-4 weeks and 5-6 weeks after onset. Clinical assessment scales used in this study were House-brackmann grade, Yanagihara unweighted grading scale and Sunnybrook facial grading system. We used Pearson's correlation for statistical analysis. RESULTS: sEMG and NCS, measured at similar times, were statistically correlated. Especially, the correlation with the forehead region was high. And sEMG and clinical assessment scale, measured at same time, were statistically correlated, especially after 5 weeks from onset. CONCLUSION: According to this study, sEMG is expected to be useful to assessment facial palsy.

13.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-716516

ABSTRACT

PURPOSE: This study was performed to compare between open reduction/internal fixation (ORIF) and minimally invasive plate osteosynthesis (MIPO) using a 3-dimensional printing model for displaced clavicular fractures. MATERIALS AND METHODS: In a retrospective study, we compared the outcomes of 21 patients treated with MIPO (Group A) with those of 22 patients treated with ORIF (Group B) between January 2013 and December 2015. After the operation, bone union was evaluated using X-ray every 4 weeks. The radiologic outcome (bone union), functional outcome (Korean shoulder scale [KSS], The University of California Los Angeles [UCLA] score), scar length, and degree of satisfaction were evaluated. RESULTS: The mean time to union was 12.1 weeks in Group A and 12.8 weeks in Group B (p=0.524). There was no significant difference in the KSS score and UCLA score between the two groups (p=0.478, p=0.698). The mean length of scar was 4.9 cm (medial 2.6 cm, lateral 2.3 cm) in Group A and 9.7 cm in Group B (p=0.001), and Group A was more satisfied than Group B with respect to scarring (p=0.001). Nonunion developed in one case in each group. Five patients in Group B had skin numbness (1 in Group A, p=0.038). CONCLUSION: There were no significant differences in the radiologic and functional results between the two groups with respect to displaced clavicle shaft fracture. However, scar satisfaction was higher in MIPO than in ORIF.


Subject(s)
Humans , Bone Plates , California , Cicatrix , Clavicle , Fracture Fixation , Hypesthesia , Printing, Three-Dimensional , Retrospective Studies , Shoulder , Skin
14.
Laboratory Animal Research ; : 216-222, 2017.
Article in English | WPRIM (Western Pacific) | ID: wpr-101378

ABSTRACT

PURPOSE: This study aims to evaluate early changes in retinal structure and BMP2 expression in the retina and crystalline lens by comparing streptozotocin-induced diabetic pigs and normal control group pigs. METHODS: Five eye samples from five diabetic Micro-pigs (Medikinetics, Pyeongtaek, Korea) and five eye samples from five control pigs bred in a specific pathogen-free area were used. Diabetes was developed through intravenous injection of nicotinamide and streptozotocin, and the average fasting glucose level was maintained at 250 mg/dL or higher for 16 weeks. To evaluate BMP2 expression in the retina and crystalline lens, Western blotting was performed. RESULTS: In Hematoxylin and Eosin staining, most diabetic pigs showed structural abnormalities in the inner plexiform layer. The number of nuclei in the ganglion cell layer within the range of 10⁴µm² was 3.78±0.60 for diabetic pigs and 5.57±1.07 for control group pigs, showing a statistically significant difference. In immunohistochemical staining, diabetic retinas showed an overall increase in BMP2 expression. In Western blotting, the average BMP2/actin level of diabetic retinas was 1.19±0.05, showing a significant increase compared to the 1.06±0.03 of the control group retinas (P=0.016). The BMP2/actin level of diabetic crystalline lenses was similar to the control group crystalline lenses (P=0.730). CONCLUSIONS: Compared to control group pigs, the number of nuclei in the inner nuclear layer of retinas from streptozotocin-induced diabetic pigs decreased, while an increase in BMP2 expression was observed in the retina of diabetic pigs.


Subject(s)
Blotting, Western , Crystallins , Diabetes Mellitus , Eosine Yellowish-(YS) , Fasting , Ganglion Cysts , Glucose , Hematoxylin , Injections, Intravenous , Lens, Crystalline , Niacinamide , Retina , Retinaldehyde , Streptozocin , Swine
15.
Obstet Gynecol Sci ; 58(5): 423-6, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26430671

ABSTRACT

Adult granulosa cell tumors (AGCTs) presenting with massive ascites and elevated serum CA-125 levels have rarely been described in the literature. An ovarian mass, massive ascites, and elevated serum CA-125 levels in postmenopausal women generally suggest a malignant ovarian tumor, particularly advanced epithelial ovarian cancer. AGCT has low (18)F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography due to its low metabolic activity. In the present report, we describe a case of an AGCT with massive ascites, elevated serum CA-125 level, and low (18)F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography.

16.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-86781

ABSTRACT

PURPOSE: To assess the distinction ability for differentiating glaucoma patients based on optic disc, retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL) measured using spectral domain optical coherence tomography (SD-OCT). Additionally, the diagnostic ability of these parameters was evaluated by comparing preperimetic glaucoma patients who frequently visited the clinic and normal patients with and without a large physiologic cup/disc (C/D) ratio. METHODS: Using SD-OCT, the optic disc, RNFL and GCIPL of preperimetic glaucoma patients were compared with normal people with and without a large C/D ratio from March, 2011 to December, 2014 at Department of Ophthalmology, Inha University Hospital. Preperimetic glaucoma was defined using the normal standard automated perimetry for glaucomatous optic nerve changes such as asymmetry of vertical C/D ratio, rim thinning, notching, excavation and RNFL defect. RESULTS: When comparing preperimetic glaucoma patients to normal people without large disc cupping, the most reliable parameter for optic disc parameters, vertical C/D ratio (0.89), showed more reliable diagnostic ability than the most reliable parameter for retinal nerve fiber, inferior RNFL thickness (0.79) and superonasal and inferonasal GCIPL thickness were the most reliable GCIPL parameters (p = 0.005 and 0.002, respectively). When comparing preperimetic glaucoma patients to normal people having a large physiologic disc cupping, average C/D ratio among optic nerve parameters, inferior RNFL thickness among RNFL thickness parameters and inferior GCIPL thickness among GCIPL parameters showed highly reliable diagnostic abilities. These 3 parameters were not statistically different (all p > 0.05) and had lower distinction ability than reported in previous studies. CONCLUSIONS: Diagnostic abilities of SD-OCT for distinguishing preperimetric glaucoma from normal people having large physiologic disc cupping were similar for optic disc, RNFL and GCIPL and showed low diagnostic ability than compared to normal people without large disc cupping.


Subject(s)
Humans , Ganglion Cysts , Glaucoma , Nerve Fibers , Ophthalmology , Optic Nerve , Retinaldehyde , Tomography, Optical Coherence , Visual Field Tests
17.
Article in English | WPRIM (Western Pacific) | ID: wpr-62646

ABSTRACT

Adult granulosa cell tumors (AGCTs) presenting with massive ascites and elevated serum CA-125 levels have rarely been described in the literature. An ovarian mass, massive ascites, and elevated serum CA-125 levels in postmenopausal women generally suggest a malignant ovarian tumor, particularly advanced epithelial ovarian cancer. AGCT has low 18F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography due to its low metabolic activity. In the present report, we describe a case of an AGCT with massive ascites, elevated serum CA-125 level, and low 18F-fluorodeoxyglucose uptake on positron emission tomography/computed tomography.


Subject(s)
Adult , Female , Humans , Ascites , Electrons , Granulosa Cell Tumor , Granulosa Cells , Ovarian Neoplasms
18.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-653984

ABSTRACT

PURPOSE: The purpose of this study is to evaluate the rate and direction of subsidence that occurred after anterior cervical discectomy and fusion using the polyetheretherketone (PEEK) cage and to analyze the risk factors of subsidence. MATERIALS AND METHODS: Thirty two patients (36 segments) who underwent anterior cervical discectomy and fusion using the PEEK cage and autologous cancellous iliac bone graft from July 2003 to November 2011 were enrolled in this study. anterior segmental height (ASH), posterior segmental height (PSH) and cage corner distance (CCD) were measured on plain radiographs. Subsidence was defined as > or =2 mm decrease in the average of ASH and PSH at the final follow up compared to that measured in the immediate postoperative period. A decrease of more than 3 mm was defined as severe subsidence for further statistical analysis. RESULTS: Subsidence of more than 2 mm was observed in 14 segments (38.9%) and severe subsidence (> or =3 mm) was observed in seven segments (19.4%). The direction of subsidence was examined by comparison of means of decreased ASH and PSH and anterior subsidence outweighed posterior subsidence (p<0.001). Examination of CCD showed that inferior subsidence was more frequent than superior subsidence (p<0.001, p=0.047). Among the suspicious risk factors for subsidence, intraoperative disc space distraction (anterior distraction: p=0.031, posterior distraction: p=0.007) and height of inserted cage (p=0.032) showed statistical significance. CONCLUSION: Considerable incidence of subsidence was observed after use of the cage. Using a cage of appropriate height and prevention of intraoperative over-distraction of disc space will be helpful to prevention of subsidence of the cage after anterior cervical discectomy and fusion using the PEEK cage.


Subject(s)
Humans , Diskectomy , Follow-Up Studies , Incidence , Postoperative Period , Risk Factors , Transplants
19.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-66853

ABSTRACT

PURPOSE: This study was performed to evaluate the impact of the lesser toe operation on the overall clinical outcomes, and to analyze the clinical results of concomitant surgery for hallux valgus and lesser toe deformities. MATERIALS AND METHODS: Forty-six cases underwent surgery for hallux valgus with concomitant lesser toe deformities were followed up for at least 1 year. Lesser toe deformities consisted of 9 crossover toes, 10 claw toes, 12 hammer toes and 15 bunionettes. Clinical evaluation was performed according to AOFAS (American Orthopaedic Foot and Ankle Society) score, patient's satisfaction score, and pain VAS (visual analogue scale) score. Hallux valgus angle (HVA), intermetatarsal angle (IMA), and period to union were measured. Preoperative expectation about lesser toe deformities, postoperative satisfaction, complication rate, hospitalization period, medical expenses, and frequency of outpatient follow-up were analyzed. RESULTS: AOFAS score, VAS score, HAV and IMA had improved significantly. On preoperative expectation of patients, correction of lesser toe deformities was ranked third, following the improvement of big toe(bunion) pain and the correction of hallux valgus. Patient's satisfaction score was average 92.8 points, and the importance of lesser toe operation was 30.2%. When compared to hallux valgus operation only, there were average 2.5 days of additional hospitalization, 2.4 times of additional outpatient follow-up, 386000 won of additional medical expenses. CONCLUSION: Combined operation for hallux valgus and concomitant lesser toe deformities showed good clinical results. When compared to hallux valgus operation only, there were longer hospitalization, more frequent follow-up, more medical expenses, more complications. However, lesser toe deformity correction in patients underwent hallux valgus operation is considerable, because of high preoperative expectation and postoperative satisfaction.


Subject(s)
Animals , Humans , Ankle , Bunion, Tailor's , Congenital Abnormalities , Follow-Up Studies , Foot , Hallux , Hallux Valgus , Hammer Toe Syndrome , Hospitalization , Outpatients , Toes
20.
Article in Korean | WPRIM (Western Pacific) | ID: wpr-46134

ABSTRACT

PURPOSE: This study was performed to evaluate the clinical outcomes of operative treatment using mini-open sinus tarsi approach for displaced intraarticular calcaneal fractures. MATERIALS AND METHODS: We studied 18 cases (16 patients) of intraarticular calcaneal fractures who were treated with sinus tarsi approach by same surgeon. The mean age of patients was 44.8 years, and mean follow-up period was 17.2 months. The measurement of Bohler angle, Gissane angle, the degree of articular surface depression, and the period to union were performed through preoperative and postoperative radiographs. The clinical evaluation was performed according to hindfoot score of the American Orthopaedic Foot and Ankle Society (AOFAS) and scale of the Creighton-Nebraska health foundation (CNHF). RESULTS: Bohler angle and Gissane angle had improved significantly from preoperative average 9.8degrees, 117.6degrees to average 22.4degrees, 113.4degrees immediate postoperatively, and had maintained to average 21.8degrees and 114.2degrees at the last follow-up. The degree of articular surface depression had improved significantly from preoperative average 5.2 mm to 1.2 mm at the last follow-up. All cases achieved bone union, and the period to union was average 10.5 weeks. AOFAS score was average 86.2 points at the last follow-up. There were 7 excellent, 9 good, and 2 fair results according to the CNHF scale. Therefore, 16 cases (88.8%) achieved satisfactory results. CONCLUSION: The minimally invasive sinus tarsi approach using headless compression screw seems to be an effective surgical method for displaced intraarticular calcaneal fractures, because of the possibility of accurate restoration of articular surface and the low risk of postoperative soft tissue complications.


Subject(s)
Animals , Humans , Ankle , Calcaneus , Depression , Follow-Up Studies , Foot , Intra-Articular Fractures
SELECTION OF CITATIONS
SEARCH DETAIL