ABSTRACT
Thirty six patients with active duodenal ulcers were studied in this double blind work. 19 received placebo and 17 Cimetidine: 1 gr./day. The endoscopic control after 21 days, showed healing in 81,2% of the cases treated with Cimetidine and in 22,2% of those with placebo. After 42 days of continous treatment with Cimetidine the healing of duodenal ulcers was 82,3% against 50% with placebo; the difference being highly statestically significant; p less than 0.01. The symptoms improved with Cimetidine revealing less diurnal and nocturnal pain complete disappearance of nausea and vomit and a significant decreased ingestion of alkali tablets.
Subject(s)
Cimetidine/therapeutic use , Duodenal Ulcer/drug therapy , Guanidines/therapeutic use , Adolescent , Adult , Cimetidine/administration & dosage , Clinical Trials as Topic , Creatinine/metabolism , Double-Blind Method , Duodenal Ulcer/diagnostic imaging , Endoscopy , Gastric Juice/metabolism , Humans , Middle Aged , Placebos/therapeutic use , Radiography , Transaminases/metabolismABSTRACT
Thirty six patients with active duodenal ulcers were studied in this double blind work. 19 received placebo and 17 Cimetidine: 1 gr./day. The endoscopic control after 21 days, showed healing in 81,2
of the cases treated with Cimetidine and in 22,2
of those with placebo. After 42 days of continous treatment with Cimetidine the healing of duodenal ulcers was 82,3
against 50
with placebo; the difference being highly statestically significant; p less than 0.01. The symptoms improved with Cimetidine revealing less diurnal and nocturnal pain complete disappearance of nausea and vomit and a significant decreased ingestion of alkali tablets.
ABSTRACT
Thirty six patients with active duodenal ulcers were studied in this double blind work. 19 received placebo and 17 Cimetidine: 1 gr./day. The endoscopic control after 21 days, showed healing in 81,2
of the cases treated with Cimetidine and in 22,2
of those with placebo. After 42 days of continous treatment with Cimetidine the healing of duodenal ulcers was 82,3
with placebo; the difference being highly statestically significant; p less than 0.01. The symptoms improved with Cimetidine revealing less diurnal and nocturnal pain complete disappearance of nausea and vomit and a significant decreased ingestion of alkali tablets.
