Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
Add more filters










Database
Language
Publication year range
1.
J Surg Case Rep ; 2023(10): rjad592, 2023 Oct.
Article in English | MEDLINE | ID: mdl-37901609

ABSTRACT

Peritoneal dialysis (PD) is the most commonly used treatment for patients with end-stage renal disease and has the advantages of simple operation and low treatment costs. However, long-term PD may lead to inguinal hernia formation, which needs to be repaired as early as possible. There are many studies on this kind of hernia, but there are few reports about how to treat recurrent hernia in PD patients. Therefore, we present a case of a female PD patient who suffered from a recurrent femoral hernia after primary hernioplasty. We successfully proceeded with treatment by laparoscopic transabdominal preperitoneal hernia repair. The patient was scheduled to receive temporary haemodialysis until the normal PD dose was restored. After 36 months of follow-up, we found that there was no recurrence of hernia, and the function of the PD catheter was normal.

2.
Exp Ther Med ; 16(1): 222-230, 2018 Jul.
Article in English | MEDLINE | ID: mdl-29896243

ABSTRACT

Diabetes mellitus (DM) is associated with an increased risk of colorectal cancer (CRC). Hyperglycemia, a chronic abnormality in diabetes, is an independent predictor of cancer-associated mortality in CRC. However, the underlying biological mechanism of hyperglycemia in CRC cells is largely unknown. In the present study, HCT-116 and HT-29 cell proliferation, apoptosis, migration and invasion were assessed. In addition, the expression of epithelial (E)-cadherin, vimentin and high-mobility group A protein 2 (HMGA2) were assessed using western blotting. The results demonstrated that high glucose (HG; 30 mmol/l) caused CRC cells to lose their epithelial morphology, with a decrease in E-cadherin and an increase in vimentin, suggesting epithelial-mesenchymal transition (EMT). Furthermore, HG significantly enhanced the cell migration and invasion of CRC cells and the expression of HMGA2. Transfection with HMGA2 small interfering RNA reversed the HG-induced changes to CRC cells. In addition, HG promoted CRC cell proliferation and suppressed apoptosis. The results of the present study suggest that hyperglycemia promotes EMT, proliferation, migration and invasion in CRC cells and may provide novel insights into the link between HG and CRC.

3.
Int J Clin Exp Pathol ; 6(11): 2569-77, 2013.
Article in English | MEDLINE | ID: mdl-24228122

ABSTRACT

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare disease of unknown etiology that typically presents as nodal disease in young children. However, it also can present in various extranodal sites and can be difficult to recognize if not considered in the differential diagnosis. Here, we report a case of appendix involvement by extranodal RDD, which occurred in a 69-year-old woman with a long duration of 12 years for intermittent right lower quadrant pain. The patient underwent a right hemicolectomy for a clinical diagnosis of appendiceal cancer. A mixed inflammatory infiltration of mature lymphocytes, plasma cells and histiocytes exhibiting emperipolesis were indentified. Other areas had storiform fibrosis and sclerosis admixed with numerous plasma cells. These histologic features combination with immunoreactivity for CD68 and S100 protein were indicative of a diagnosis of extranodal RDD. We discuss the clinical, pathologic findings as well as differential diagnoses and consideration of a possible relationship of this entity to IgG4-related lesion.


Subject(s)
Appendix/pathology , Histiocytosis, Sinus/diagnosis , Immunoglobulin G/analysis , Lymph Nodes/pathology , Aged , Antigens, CD/analysis , Antigens, Differentiation, Myelomonocytic/analysis , Appendiceal Neoplasms/diagnosis , Appendix/chemistry , Appendix/surgery , Biomarkers/analysis , Biopsy , Colectomy , Diagnostic Errors , Female , Fibrosis , Histiocytosis, Sinus/pathology , Histiocytosis, Sinus/surgery , Humans , Immunohistochemistry , Lymph Nodes/chemistry , Lymph Nodes/surgery , Mesentery , Predictive Value of Tests , S100 Proteins/analysis , Sclerosis , Time Factors , Tomography, X-Ray Computed
SELECTION OF CITATIONS
SEARCH DETAIL
...