1.
Improvement in the yield of oral poliovirus vaccine (Sabin strains) produced in human diploid cells.
Dev Biol Stand
; 41: 183-5, 1978.
Article
in English
| MEDLINE
| ID: mdl-753650
ABSTRACT
When stationary cultures of human diploid cells in conventional Roux bottles were replaced by the development of cells in roller bottles, the yield of poliovirus, Sabin strains type 1 and 2, showed an increase of 0.5 to 1 log10. No significant difference was noticed in the yield of these viruses cultured in WI-38 and MRC-5 human diploid cells.
