ABSTRACT
The objective of the present study was to evaluate the immune status of patients with chronically recurring polypous rhinosinusitis (CRPS) for the identification of the key markers of immune disorders. Assessment of the efficiency of traditional therapy during the postoperative period demonstrated that it was very low in terms of beneficial effect on the major components of the immune system, T and B lymphocytes. Determination of the frequency of immune disorders during irradiation of autoblood with ultraviolet light and plasmapheresis in the postoperative period and evaluation of "true" effects of these treatments revealed their significant quantitative immunostimulating action. Integral evaluation (rank-sum analysis) demonstrated similar therapeutic efficiency of the two methods.
Subject(s)
Blood Transfusion, Autologous/methods , Blood/radiation effects , Immunotherapy/methods , Nasal Polyps/therapy , Plasmapheresis/methods , Rhinitis/therapy , Sinusitis/therapy , Adult , Female , Humans , Male , Middle Aged , Nasal Polyps/immunology , Rhinitis/immunology , Sinusitis/immunology , Treatment Outcome , Ultraviolet RaysABSTRACT
Early plastic repair of severe tracheal defects after previous decannulation of the latter in x-ray confirmed efficacy of aspiration flow system of fat spaces of the neck and mediastinum and stability of the patient's condition. This therapeutic policy stops cross-over contamination of fat spaces of the neck, mediastinum, tracheobronchial tree; reduces cost of therapy; facilitates cleansing of foci of purulent surgical infection; shortens time to reconstruction for soft tissue defect of the neck.
Subject(s)
Cellulitis/complications , Mediastinitis/complications , Neck , Plastic Surgery Procedures/methods , Tracheal Diseases/surgery , Cellulitis/surgery , Humans , Mediastinitis/surgery , Prosthesis Implantation , Retrospective Studies , Time Factors , Tracheal Diseases/etiology , Treatment OutcomeABSTRACT
Such immunological indices as the number of T- and B-cells in a rosette-formation test, T-cell sensitivity to theophylline, quantity of the main Ig classes and CIC were investigated in 43 patients with primary chronic polypous rhinosinusitis and 34 patients with recurrent polypous rhinosinusitis. Elevated levels were registered of IgG, IgM, IgA and CIC this evidencing hyperfunction of B-cell immunity. Immunocorrection with sodium nucleinate in surgical treatment of sinusitides contributed to more rapid recovery of the patients.
