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1.
PLoS One ; 19(5): e0302880, 2024.
Article in English | MEDLINE | ID: mdl-38718092

ABSTRACT

Gastrointestinal (GI) cancer is leading general tumour in the Gastrointestinal tract, which is fourth significant reason of tumour death in men and women. The common cure for GI cancer is radiation treatment, which contains directing a high-energy X-ray beam onto the tumor while avoiding healthy organs. To provide high dosages of X-rays, a system needs for accurately segmenting the GI tract organs. The study presents a UMobileNetV2 model for semantic segmentation of small and large intestine and stomach in MRI images of the GI tract. The model uses MobileNetV2 as an encoder in the contraction path and UNet layers as a decoder in the expansion path. The UW-Madison database, which contains MRI scans from 85 patients and 38,496 images, is used for evaluation. This automated technology has the capability to enhance the pace of cancer therapy by aiding the radio oncologist in the process of segmenting the organs of the GI tract. The UMobileNetV2 model is compared to three transfer learning models: Xception, ResNet 101, and NASNet mobile, which are used as encoders in UNet architecture. The model is analyzed using three distinct optimizers, i.e., Adam, RMS, and SGD. The UMobileNetV2 model with the combination of Adam optimizer outperforms all other transfer learning models. It obtains a dice coefficient of 0.8984, an IoU of 0.8697, and a validation loss of 0.1310, proving its ability to reliably segment the stomach and intestines in MRI images of gastrointestinal cancer patients.


Subject(s)
Gastrointestinal Neoplasms , Gastrointestinal Tract , Magnetic Resonance Imaging , Humans , Magnetic Resonance Imaging/methods , Gastrointestinal Neoplasms/diagnostic imaging , Gastrointestinal Neoplasms/pathology , Gastrointestinal Tract/diagnostic imaging , Semantics , Image Processing, Computer-Assisted/methods , Female , Male , Stomach/diagnostic imaging , Stomach/pathology
2.
Diagnostics (Basel) ; 13(19)2023 Oct 09.
Article in English | MEDLINE | ID: mdl-37835895

ABSTRACT

Glomeruli are interconnected capillaries in the renal cortex that are responsible for blood filtration. Damage to these glomeruli often signifies the presence of kidney disorders like glomerulonephritis and glomerulosclerosis, which can ultimately lead to chronic kidney disease and kidney failure. The timely detection of such conditions is essential for effective treatment. This paper proposes a modified UNet model to accurately detect glomeruli in whole-slide images of kidney tissue. The UNet model was modified by changing the number of filters and feature map dimensions from the first to the last layer to enhance the model's capacity for feature extraction. Moreover, the depth of the UNet model was also improved by adding one more convolution block to both the encoder and decoder sections. The dataset used in the study comprised 20 large whole-side images. Due to their large size, the images were cropped into 512 × 512-pixel patches, resulting in a dataset comprising 50,486 images. The proposed model performed well, with 95.7% accuracy, 97.2% precision, 96.4% recall, and 96.7% F1-score. These results demonstrate the proposed model's superior performance compared to the original UNet model, the UNet model with EfficientNetb3, and the current state-of-the-art. Based on these experimental findings, it has been determined that the proposed model accurately identifies glomeruli in extracted kidney patches.

3.
Diagnostics (Basel) ; 13(7)2023 Apr 02.
Article in English | MEDLINE | ID: mdl-37046538

ABSTRACT

Brain tumor diagnosis at an early stage can improve the chances of successful treatment and better patient outcomes. In the biomedical industry, non-invasive diagnostic procedures, such as magnetic resonance imaging (MRI), can be used to diagnose brain tumors. Deep learning, a type of artificial intelligence, can analyze MRI images in a matter of seconds, reducing the time it takes for diagnosis and potentially improving patient outcomes. Furthermore, an ensemble model can help increase the accuracy of classification by combining the strengths of multiple models and compensating for their individual weaknesses. Therefore, in this research, a weighted average ensemble deep learning model is proposed for the classification of brain tumors. For the weighted ensemble classification model, three different feature spaces are taken from the transfer learning VGG19 model, Convolution Neural Network (CNN) model without augmentation, and CNN model with augmentation. These three feature spaces are ensembled with the best combination of weights, i.e., weight1, weight2, and weight3 by using grid search. The dataset used for simulation is taken from The Cancer Genome Atlas (TCGA), having a lower-grade glioma collection with 3929 MRI images of 110 patients. The ensemble model helps reduce overfitting by combining multiple models that have learned different aspects of the data. The proposed ensemble model outperforms the three individual models for detecting brain tumors in terms of accuracy, precision, and F1-score. Therefore, the proposed model can act as a second opinion tool for radiologists to diagnose the tumor from MRI images of the brain.

4.
PLoS One ; 15(5): e0231465, 2020.
Article in English | MEDLINE | ID: mdl-32365123

ABSTRACT

Learning using the Internet or training through E-Learning is growing rapidly and is increasingly favored over the traditional methods of learning and teaching. This radical shift is directly linked to the revolution in digital computer technology. The revolution propelled by innovation in computer technology has widened the scope of E-Learning and teaching, whereby the process of exchanging information has been made simple, transparent, and effective. The E-Learning system depends on different success factors from diverse points of view such as system, support from the institution, instructor, and student. Thus, the effect of critical success factors (CSFs) on the E-Learning system must be critically analyzed to make it more effective and successful. This current paper employed the analytic hierarchy process (AHP) with group decision-making (GDM) and Fuzzy AHP (FAHP) to study the diversified factors from different dimensions of the web-based E-Learning system. The present paper quantified the CSFs along with its dimensions. Five different dimensions and 25 factors associated with the web-based E-Learning system were revealed through the literature review and were analyzed further. Furthermore, the influence of each factor was derived successfully. Knowing the impact of each E-Learning factor will help stakeholders to construct education policies, manage the E-Learning system, perform asset management, and keep pace with global changes in knowledge acquisition and management.


Subject(s)
Academic Success , Computer-Assisted Instruction , Curriculum/standards , Internet , Learning/physiology , Computer-Assisted Instruction/methods , Computer-Assisted Instruction/standards , Computer-Assisted Instruction/supply & distribution , Digital Divide/trends , Fuzzy Logic , Humans , Implementation Science , Internet/organization & administration , Internet/standards , Internet/supply & distribution , Internet Access/statistics & numerical data , Internet Access/trends , Knowledge , School Teachers/organization & administration , School Teachers/standards , Students/psychology , Students/statistics & numerical data , Teacher Training/methods , Teacher Training/organization & administration , Teacher Training/standards
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