ABSTRACT
Autonomic imbalance is seen in hypertensive. This study was designed to compare heart rate variability in normotensive and hypertensive Indian adults. HRV records beat to beat variation in R-R intervals in milliseconds in electrocardiogram. Lead II ECG was recorded and a 5 minutes' stationary, artifacts free recording was selected for data analysis. HRV measures like total power was significantly less in hypertensive (303.37 ± 438.1) as compared to normotensive (534.16 ± 818.41). Standard deviation of normal-to-normal RR intervals was significantly reduced in hypertensive. A significant reduction of HRV was seen in hypertensive as compared to normotensive.
Subject(s)
Autonomic Nervous System Diseases , Hypertension , Humans , Adult , Heart Rate/physiology , Hypertension/diagnosis , Blood Pressure/physiology , ElectrocardiographyABSTRACT
Studies conducted earlier have found that vascular sympathetic reactivity to isometric handgrip exercise is either low or high in adolescents with higher blood pressure (Hypertensives) as compared to adolescents with relatively lower blood pressure (Normotensive). The current study was conducted to determine the correlation of vascular sympathetic reactivity to isometric handgrip exercise with blood pressure in Gujarati Indian adolescents so as to understand the pathogenesis and/consequences of Hypertension in this population. A cross-sectional study was conducted on 651 Gujarati Indian adolescents (285 girls, 366 boys) of age group 13-19 years. Blood pressure was measured by oscillometry and vascular sympathetic reactivity (Percentage rise in Diastolic Blood Pressure, %RDBP) was assessed using isometric handgrip test. Pearson's correlation coefficient was determined to study the correlation between %RDBP and blood pressure. In both girls and boys, %RDBP showed significant negative correlation with resting SBP, DBP and MAP. The study thus indicates that an inverse association exist between arterial blood pressure and vascular sympathetic reactivity to isometric handgrip exercise in Gujarati Indian adolescents.
