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1.
J Investig Med High Impact Case Rep ; 12: 23247096241242237, 2024.
Article in English | MEDLINE | ID: mdl-38577756

ABSTRACT

Plasmacytoma is a rare plasma cell dyscrasia that grows in bones or soft tissues such as the pharynx. Soft tissue plasmacytomas are rare, and a higher burden has been reported in the upper aero-digestive tract, often manifesting as hoarseness, dysphagia, or odynophagia. Due to their rarity, extramedullary plasmacytomas (EMPs) have unknown prognostic factors, and guidelines for optimal management are still lacking. However, radiation therapy and surgery have been used with positive outcomes. Herein, we describe a unique case of plasmacytoma of the pharyngeal tissue in a male patient with a history of HIV disease. The patient completed 28 sessions of radiation therapy, resulting in an improvement in his throat pain and hoarseness. Given the patient's age and lack of traditional risk factors for head and neck cancers, his hoarseness and odynophagia proved to be a diagnostic conundrum. Although infrequent, soft tissue plasmacytomas should be considered in the differential diagnosis of head and neck tumors.


Subject(s)
Head and Neck Neoplasms , Plasmacytoma , Humans , Male , Plasmacytoma/diagnosis , Plasmacytoma/pathology , Plasmacytoma/radiotherapy , Pharynx/pathology , Hoarseness/etiology
2.
J Investig Med High Impact Case Rep ; 11: 23247096231220466, 2023.
Article in English | MEDLINE | ID: mdl-38130119

ABSTRACT

Tuberculous bronchopleural fistula (BPF) is a rare and potentially life-threatening complication of pulmonary tuberculosis, in which abnormal connections form between the bronchial tree and the pleural space. These abnormal connections allow air and secretions to pass from the lungs into the pleural space, causing a range of symptoms from benign cough to acute tension pneumothorax. The management of tuberculous BPF requires an individualized approach based on the patient's condition and response to treatment. Anti-tuberculosis therapy is essential for controlling the active tuberculosis infections. Intercostal drainage and suction are also commonly used to drain air and fluid from the pleural space, providing relief from the symptoms. For some patients, more invasive surgeries, such as decortication, thoracoplasty or pleuropneumonectomy are required to definitively close the fistula when medical management alone is insufficient. Herein, we describe a rare case of tuberculous BPF in a young adult female, who was treated with anti-tuberculosis medications and open thoracotomy.


Subject(s)
Bronchial Fistula , Pleural Diseases , Tuberculosis , Humans , Young Adult , Bronchial Fistula/etiology , Bronchial Fistula/therapy , Lung/surgery , Pleural Diseases/therapy , Pleural Diseases/etiology , Pneumonectomy/adverse effects , Tuberculosis/complications , Tuberculosis/therapy , Female , Antitubercular Agents/therapeutic use
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