Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 6 de 6
Filter
Add more filters










Database
Language
Publication year range
1.
Occup Ther Health Care ; 37(4): 648-663, 2023 Oct.
Article in English | MEDLINE | ID: mdl-35357275

ABSTRACT

Using an integrative review methodology, this paper describes the current literature on the use of telehealth technology to conduct occupational therapy home assessments. Searches of ProQuest Health and Medicine, PubMed and CINAHL accessed articles from January 2001 to 18 April 2021. Based on the screening and eligibility criteria, 10 articles published in English were included in the review. Three primary types of studies were identified: the feasibility of using telehealth technology to conduct home assessments; the efficiency of using telehealth technology to perform home assessments; and patient and therapist satisfaction using telehealth technology. This review ascertained that occupational therapy home assessments can be performed using telehealth technology, they are an efficient alternative to in-person assessments, and home assessments conducted via telehealth can be effective in achieving patient outcomes. Satisfaction with the use of telehealth, as an alternative service delivery model, has been identified by both patients and occupational therapists. The use of telehealth technology can increase the capacity of the occupational therapy profession to carry out home assessments although in-person home assessment is more accurate in detecting hazards in the home.


Subject(s)
Occupational Therapy , Telemedicine , Humans , Telemedicine/methods , Personal Satisfaction , Occupational Therapists
2.
Bioorg Chem ; 59: 145-50, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25797804

ABSTRACT

SK-658 is a potent histone deacetylase (HDAC) inhibitor that showed higher activity than SAHA due to the presence of extended hydrophobic group. We designed and synthesized thioester and SS-hybrid bearing SK-658 analogs as HDAC inhibitors. All the compounds were active in nano molar range and showed higher inhibitory activity than SAHA and SK-658. Among these, disulfide compounds showed the highest activity.


Subject(s)
Histone Deacetylase Inhibitors/chemistry , Histone Deacetylase Inhibitors/pharmacology , Hydroxamic Acids/chemistry , Hydroxamic Acids/pharmacology , Binding Sites , Histone Deacetylase Inhibitors/chemical synthesis , Histone Deacetylases/chemistry , Histone Deacetylases/metabolism , Humans , Models, Molecular , Structure-Activity Relationship , Zinc/metabolism
3.
J Environ Sci Health B ; 49(12): 938-44, 2014.
Article in English | MEDLINE | ID: mdl-25310809

ABSTRACT

Antioxidant activity in edible fruits is an important characteristic in the choice of fruits for human consumption, and has profound influence on nutrition and health. Two pharmacologically active triterpenoids, ß-sitosterol and lupeol, and the powerful flavan-3-ol antioxidant, (+)-catechin, were isolated from the edible fruits of Harpephyllum caffrum while a mixture of cardanols, an alkyl p-coumaric acid ester, and (+)-catechin were isolated from the stem bark. This is the first report of these compounds being isolated from this plant. The antioxidant capacity of (+)-catechin was higher than the other isolated compounds as well as the known antioxidant, ascorbic acid.


Subject(s)
Anacardiaceae/chemistry , Antioxidants/isolation & purification , Phenols/isolation & purification , Phenols/pharmacology , Antioxidants/chemistry , Coumaric Acids/isolation & purification , Coumaric Acids/pharmacology , Flavonoids/chemistry , Flavonoids/isolation & purification , Flavonoids/pharmacology , Fruit/chemistry , Magnetic Resonance Spectroscopy , Molecular Structure , Pentacyclic Triterpenes/isolation & purification , Pentacyclic Triterpenes/pharmacology , Phenols/chemistry , Plant Bark/chemistry , Plants, Medicinal/chemistry , Propionates , Sitosterols/isolation & purification , Sitosterols/pharmacology
4.
Phytochemistry ; 83: 136-43, 2012 Nov.
Article in English | MEDLINE | ID: mdl-22898386

ABSTRACT

Two A-seco-limonoids, accorded the trivial names, uguenensene and uguenensone and a C-7 prenylated flavonoid, uguenenprenol were isolated from Vepris uguenensis (Rutaceae). In addition, 11 known compounds, niloticin, chisocheton A, kihadalactone A, limonyl acetate, methyl uguenenoate, 7-O-methylaromadenrin, flindersiamine, 8α,11-elemodiol, tricoccin S13 acetate, skimmianine, and lupeol were isolated. The structures of the compounds were elucidated and characterized by spectroscopic analyses (NMR, GC-MS and IR). Antioxidant activity of the isolated compounds showed that uguenenprenol and 7-O-methylaromadenrin are good antioxidant agents. Significantly high antioxidant activity was also exhibited by 8α,11-elemodiol, which was 72% at 250 µg mL⁻¹ and 57% at 15.62 µg mL⁻¹ when tested with the deoxyribose method. The two liminoids fit nicely into the biosynthetic pathway from niloticin to methyl uguenenoate.


Subject(s)
Antioxidants/pharmacology , Flavonoids/pharmacology , Limonins/pharmacology , Oxidative Stress/drug effects , Reactive Oxygen Species/metabolism , Rutaceae/chemistry , Antioxidants/chemistry , Antioxidants/isolation & purification , Flavonoids/chemistry , Flavonoids/isolation & purification , Limonins/chemistry , Limonins/isolation & purification , Molecular Conformation
5.
Mar Pollut Bull ; 48(7-8): 624-49, 2004 Apr.
Article in English | MEDLINE | ID: mdl-15041420

ABSTRACT

The history of aquatic environmental pollution goes back to the very beginning of the history of human civilization. However, aquatic pollution did not receive much attention until a threshold level was reached with adverse consequences on the ecosystems and organisms. Aquatic pollution has become a global concern, but even so, most developing nations are still producing huge pollution loads and the trends are expected to increase. Knowledge of the pollution sources and impacts on ecosystems is important not only for a better understanding on the ecosystem responses to pollutants but also to formulate prevention measures. Many of the sources of aquatic pollutions are generally well known and huge effort has been devoted to the issue. However, new concepts and ideas on environmental pollution are emerging (e.g., biological pollution) with a corresponding need for an update of the knowledge. The present paper attempts to provide an easy-to-follow depiction on the various forms of aquatic pollutions and their impacts on the ecosystem and organisms.


Subject(s)
Ecosystem , Fisheries , Models, Theoretical , Water Pollutants, Chemical/analysis , Water Pollution/prevention & control , Eutrophication , Oceans and Seas
6.
Mar Pollut Bull ; 48(5-6): 471-85, 2004 Mar.
Article in English | MEDLINE | ID: mdl-14980464

ABSTRACT

The present study aimed to quantify the water and sediment quality and growth and production parameters and to establish nutrient budgets for an average of five selected semi-intensive shrimp ponds in Bangladesh over a growing cycle. Physico-chemical parameters of water and sediments were measured and analyzed by standard methods. Gross yield (kg ha-1) of shrimp was calculated from the stocking and harvesting data. Finally, a partial nutrient mass budget for N and P was calculated. Most of the parameters of water and sediments correlated significantly with each other suggesting a high degree of interactions between different parameters in the system. Significantly higher concentrations of all species of nitrogenous nutrients were recorded in the effluent waters than that entering into the ponds. Therefore, a high loading and net output of nitrogenous nutrients in effluent waters was documented. The study also indicated a net discharge of solids and minerals through effluent loading. However, significantly lower concentrations of phosphorus in the effluent water indicated a net retention and trapping of phosphatic nutrients in the environment. Total production ranged between 532.0 and 697.0 kg ha-1 cycle-1 and P. monodon production between 484.0 and 562.0 kg ha-1 cycle-1. Ponds gained nitrogen primarily from intake water (55%) and fertilizers (29%), and nitrogen was lost primarily from water exchange (78%) and harvested shrimp (12%). Phosphorus gain occurred mostly from intake water (52%) and fertilizers (25%), and phosphorus was lost primarily from water exchange (52%) and harvested shrimp (3.3%). About 10% of input nitrogen and 44% of phosphorus were not accounted for in measured losses, and presumably were fixed or metabolized in the system. On average, 78 g N was discharged to and 25 g P was removed from the surrounding water by the system for each kilogram of shrimp produced. Mean conversion of feed nitrogen and phosphorus to shrimp flesh averaged 74% and 40%, respectively. It was concluded that semi-intensive systems serve as net supplier of N to and net remover of P from the surrounding water.


Subject(s)
Aquaculture , Eutrophication , Geologic Sediments/chemistry , Nitrogen/analysis , Water Pollutants/analysis , Animals , Bangladesh , Environmental Monitoring , Nitrogen/metabolism , Particle Size , Penaeidae , Phosphorus/analysis
SELECTION OF CITATIONS
SEARCH DETAIL
...