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1.
J Pediatric Infect Dis Soc ; 8(1): 83-86, 2019 Mar 28.
Article in English | MEDLINE | ID: mdl-30016451

ABSTRACT

Kingella kingae typically causes musculoskeletal infection in young children between the ages of 6 months and 4 years who may be in close contact with other similarly aged children who are colonized with the organism in their oropharynx. Kingella infections have rarely been described in older individuals with chronic medical conditions or immune compromise. This is a case report of a healthy, older child who developed an invasive infection due to Kingella kingae. Clinical and laboratory details are provided of an otherwise healthy 11-year-old female who developed an acute onset of septic arthritis of her shoulder. The organism was identified by culture and 16S polymerase chain reaction. Her clinical course necessitated an antibiotic change after the organism was correctly identified. The affected child had close contact with a 2-year-old sibling who recently had a viral upper respiratory infection. This case illustrates the potential for Kingella kingae to rarely cause invasive infection in older, healthy children. Supplemental laboratory techniques may be helpful to identify this organism. Although it is reasonable to limit the antibiotic spectrum for older children, clinicians should be aware of this possibility, particularly if there is a history of close contact with young children.


Subject(s)
Arthritis, Infectious/diagnosis , Kingella kingae/isolation & purification , Neisseriaceae Infections/diagnosis , Shoulder/microbiology , Age of Onset , Anti-Bacterial Agents/therapeutic use , Arthritis, Infectious/drug therapy , Arthritis, Infectious/microbiology , Biopsy, Needle , Child , Clindamycin/therapeutic use , Female , Humans , Neisseriaceae Infections/drug therapy , Shoulder/diagnostic imaging
2.
J Knee Surg ; 31(7): 605-609, 2018 Aug.
Article in English | MEDLINE | ID: mdl-29514375

ABSTRACT

Venous thromboembolic disease (VTED) is a major cause of morbidity and mortality after total knee arthroplasty (TKA). Current VTED prophylaxis protocols consist of early mobilization, mechanical compression devices, and pharmacologic agents. Venous phasic flow-regulated below-knee devices are generally favored, but the optimal duration and method of mechanical prophylaxis is unknown. Risk stratification models have been developed to guide pharmacologic prophylaxis. For patients with standard VTED risk profile, aspirin has become increasingly popular. Recent studies have validated the efficacy, relatively low bleeding risks, and cost-effectiveness of aspirin in the patients with standard risk profile. Current evidence suggests that the newer oral anticoagulants, including the factor Xa and the direct thrombin inhibitors, are effective for the reduction of postoperative VTED but may be associated with increased bleeding and wound complication rates.


Subject(s)
Anticoagulants/administration & dosage , Arthroplasty, Replacement, Knee/adverse effects , Venous Thromboembolism/prevention & control , Anticoagulants/adverse effects , Aspirin/administration & dosage , Aspirin/adverse effects , Chemoprevention , Early Ambulation , Hemorrhage/chemically induced , Heparin, Low-Molecular-Weight/administration & dosage , Heparin, Low-Molecular-Weight/adverse effects , Humans , Intermittent Pneumatic Compression Devices , Venous Thromboembolism/etiology , Warfarin/administration & dosage , Warfarin/adverse effects , Wound Healing/drug effects
3.
J Orthop Trauma ; 31(4): e121-e126, 2017 Apr.
Article in English | MEDLINE | ID: mdl-28328732

ABSTRACT

OBJECTIVES: To evaluate a previously described technique using the inherent anteversion of intramedullary nail (IMN) to avoid malrotation in comminuted femur fractures and describe the use of magnetic resonance imaging (MRI) as an alternative method for assessing postoperative femoral version. DESIGN: Prospective consecutive cohort study. SETTING: Level I trauma center. PATIENT/PARTICIPANTS: Twenty-five consecutive patients with comminuted femur fractures (Winquist III/IV, OTA/AO 32-B/32-C) treated by a single surgeon with IMN between September 1, 2011, and February 28, 2015. INTERVENTION: IMN on a fracture table with intraoperative femoral version set by the inherent version of the implant. All patients received a postoperative computed tomography (CT) or MRI to assess femoral version. MAIN OUTCOME MEASUREMENTS: Mean difference in postoperative femoral anteversion (DFA) between injured limb and uninjured limb as measured by CT or MRI. Mean difference in postoperative femoral version of the injured femur from the inherent version of the implant (12 degrees) was measured with CT or MRI. RESULTS: The mean postoperative DFA was 9.1 ± 5.6 degrees. Postoperative DFA greater than 15 degrees was found in 2 (8.0%) patients. Mean difference in postoperative version of the injured femur from the inherent 12 degrees of the implant was 7.1 ± 5.4 degrees. Patients tolerated MRI studies well. CONCLUSIONS: Our previously described technique using the inherent anteversion of an IMN is effective and leads to a very low rate of malrotation, even in highly comminuted fractures. The technique is particularly useful in treating bilateral femur fractures. MRI can be used safely and effectively to assess anteversion after fixation of femur fractures. LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.


Subject(s)
Bone Malalignment/prevention & control , Femoral Fractures/surgery , Fracture Fixation, Intramedullary/adverse effects , Fracture Fixation, Intramedullary/methods , Fractures, Comminuted/surgery , Joint Deformities, Acquired/etiology , Joint Deformities, Acquired/prevention & control , Adult , Aged , Aged, 80 and over , Bone Malalignment/etiology , Female , Femoral Fractures/complications , Femoral Fractures/diagnostic imaging , Fractures, Comminuted/complications , Fractures, Comminuted/diagnostic imaging , Humans , Magnetic Resonance Imaging/methods , Male , Middle Aged , Reproducibility of Results , Sensitivity and Specificity , Treatment Outcome
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