Impact of green HRM practices on sustainable performance: mediating role of green innovation, green culture, and green employees' behavior.

The concept of sustainability in the context of human resource management (HRM), or more precisely, green HRM, has significantly transformed in recent years. Human resources are an important and valuable asset of a firm. In this research, green HRM is concentrated on the areas where HRM is held accountable for the company's sustainability initiatives. The research examines the effects of green HRM on organizational performance in China while considering the mediating roles of green innovation (GI), green employee behavior (GEB), and organizational culture. The data was gathered from 316 HR specialists working in various Chinese manufacturing businesses to meet the study's goals. A self-administered questionnaire utilizing the preexisting scale is used to obtain the data (detail is provided in Table 1). The smart PLS 4 structural equation modeling approach is applied for the data analysis. The study results indicate that green HRM practices influence green innovation (GI), green culture (GC), and green employee behavior (GEB). Furthermore, results also suggest that GI, GC, and GEB influence the organization's sustainable performance (SP). The research has several theoretical, methodological, and practical ramifications for many stakeholders, including the Chinese security exchange commissions, firms' senior management, academics, and HR specialists.

Bartonella henselae Infective Endocarditis: A Rare Cause of Pauci-Immune Necrotizing Glomerulonephritis-A Case Report.

Rationale: Bartonella sp. are the most common causes of culture-negative infective endocarditis (IE) cases in the United States. Although, infection-related glomerulonephritis can frequently mimic primary vasculitis due to pauci-immune pattern, majority of previously reported cases of Bartonella henselae-associated glomerulonephritis have immune-complex deposits on immunofluorescence. We present a rare case of B henselae IE-related pauci-immune necrotizing glomerulonephritis. Timely recognition of this atypical presentation led to appropriately directed medical therapy. Presenting concerns of the patient: A 33-year-old Caucasian male with a history of human immunodeficiency virus (HIV) on highly active antiretroviral therapy (HAART), alcohol abuse, previous subarachnoid hemorrhage (SAH), and recent wisdom tooth extraction (on amoxicillin) was transferred from an outside hospital for further evaluation of severe headache. He was diagnosed with an SAH and right anterior cerebral artery mycotic aneurysm. The serum creatinine at the outside hospital was 292 umol/L (3.3 mg/dL) with a previously normal baseline around 2 years ago. The serum creatinine at our institution was 256 umol/L (3.0 mg/dL). The urinalysis demonstrated +100 protein, +3 blood and 29 red blood cells/high power field. The urine protein creatinine ratio (UPC) was 1.7 g/g. Serologic evaluation was positive for a low C4 10.2 mg/dL, elevated rheumatoid factor 40 IU/mL and an elevated proteinase 3 (PR-3) antineutrophilic cytoplasmic antibodies (ANCA Ab) 4.0 U/mL. A transesophageal echocardiogram (TEE) showed echo densities on both mitral and aortic valve. Blood cultures were negative. Further serologic evaluation was positive for B henselae IgG titer of 1:2560 (normal <1:320) with a negative IgM titer. Diagnoses: A percutaneous kidney biopsy revealed pauci-immune necrotizing glomerulonephritis, with 14/16 glomeruli globally sclerotic, and 2 glomeruli with active segmental necrotizing lesions. There was no evidence of immune-complex deposition on immunofluorescence or electron microscopy. Clinical findings were consistent with B henselae IE associated mycotic aneurysm and necrotizing glomerulonephritis. Intervention: Empiric treatment for an active glomerulonephritis with immunosuppressive agents was deferred on admission, given concern for an underlying infectious process and mycotic aneurysms in an HIV-positive patient. He received antibiotic treatment with doxycycline and ceftriaxone with gentamicin for synergy. Despite this, the mitral and aortic valve regurgitation worsened, and he developed congestive heart failure requiring aortic valve replacement and mitral valve repair. The explanted aortic valve was positive for B henselae by polymerase chain reaction (PCR) confirming the diagnosis of B henselae IE. Outcomes: Immunosuppression was deferred due to timely identification of an atypical presentation of B henselae-associated ANCA antibodies-positive, pauci-immune necrotizing glomerulonephritis. A course of antibiotic treatment resulted in improved renal functions along with undetectable B henselae and PR3 Ab titers. The serum creatinine decreased to 176 umol/L (2 mg/dL) and remained stable 12 months after discharge. Teaching points: B henselae IE should be suspected in patients with pauci-immune necrotizing glomerulonephritis and culture-negative IE. This is imperative for optimal decision making in the management of such patients. Having high clinical suspicion can avoid unnecessary and potentially deleterious use of immunosuppressive agents.

Justification: La bactérie Bartonella sp est la cause la plus fréquente des cas d'endocardite infectieuse (EI) à culture négative aux États-Unis. Bien qu'il arrive souvent que les glomérulonéphrites, en raison de leur schéma auto-immun, puissent ressembler à des vascularites primaires, la majorité des cas précédemment signalés de glomérulonéphrites associées à B. henselae présentent des dépôts de complexes immuns sur immunofluorescence. Nous présentons un cas rare d'endocardite infectieuse à B. henselae associée à une glomérulonéphrite pauci-immune nécrosante. La reconnaissance rapide de cette présentation atypique a conduit à un traitement médical bien dirigé. Présentation du cas: Un homme caucasien de 33 ans atteints du virus de l'immunodéficience humaine (VIH) sous traitement antirétroviral hautement actif (HAART) qui avait été transféré d'un autre hôpital pour une évaluation plus approfondie de céphalées intenses. Le patient avait des antécédents d'abus d'alcool, d'une hémorragie sous-arachnoïdienne (HSA) antérieure et d'une récente extraction de dents de sagesse (prise d'amoxicilline). Le patient a reçu un diagnostic d'HSA et d'anévrisme mycotique de l'artère cérébrale antérieure droite. Le taux de créatinine sérique mesuré à l'hôpital externe était de 292 umol/L (3,3 mg/dL); le patient présentait une valeur normale environ 2 ans auparavant. Le taux de créatinine sérique mesuré dans notre établissement était de 256 umol/L (3,0 mg/dL). L'analyze d'urine a révélé un décompte supérieur à 100 pour les protéines et de + 3 pour le sang avec 29 globules rouges/champ à puissance élevée. Le rapport protéine/créatinine urinaire (UPC) était de 1,7 g/g. L'évaluation sérologique était positive pour un faible taux de C4 (10,2 mg/dL), un taux élevé de facteur rhumatoïde (40 UI/mL) et un taux élevé (4,0 U/mL) d'anticorps anti-cytoplasme des neutrophiles (ANCA) anti-protéinase 3 (PR-3). Une échocardiographie transœsophagienne (ÉTO) a montré des végétations sur les valves mitrale et aortique. Les hémocultures étaient négatives. Une évaluation sérologique plus poussée s'est avérée positive pour le titer d'IgG de B. henselae, avec un rapport de 1:2560 (normale = inférieur à 1:320), et négative pour le titer d'IgM. Diagnostics: Une biopsie rénale percutanée a révélé une glomérulonéphrite pauci-immune nécrosante avec un taux de 14/16 glomérules sclérotiques et 2 glomérules présentant des lésions segmentaires nécrosantes actives. Aucune preuve de dépôt de complexe immun n'a été observée par immunofluorescence ou par microscopie électronique. Les résultats cliniques correspondaient à une endocardite infectieuse à B. henselae associée à l'anévrisme mycotique et à la glomérulonéphrite nécrosante. Intervention: Le traitement empirique d'une glomérulonéphrite active avec des agents immunosuppresseurs a été reporté lors de l'admission, en raison de la crainte d'un processus infectieux sous-jacent et d'anévrismes mycotiques chez un patient séropositif. Le patient a reçu un traitement antibiotique de doxycycline et de ceftriaxone avec gentamicine pour la synergie. Malgré cette intervention, la régurgitation des valves mitrale et aortique s'est aggravée et le patient a développé une insuffisance cardiaque congestive qui a nécessité le remplacement de la valve aortique et la réparation de la valve mitrale. Une analyze par PCR (réaction en chaîne de la polymérase) sur la valve aortique explantée s'est avérée positive pour B. henselae, ce qui a confirmé le diagnostic d'endocardite infectieuse à B. henselae. Résultats: Le traitement immunosuppresseur a été reporté en raison de l'identification opportune d'une présentation atypique de glomérulonéphrite pauci-immune nécrosante positive pour les anticorps anti-cytoplasme des neutrophiles (ANCA) associés à B. henselae. Un traitement antibiotique a permis d'améliorer la fonction rénale et a ramené les titres de B. henselae et d'Ac PR3 à des niveaux indétectables. Le taux de créatinine sérique est passé à 176 umol/L (2 mg/dL) et est demeuré stable 12 mois après le congé du patient. Enseignements tirés: L'endocardite infectieuse associée à B. henselae doit être suspectée chez les patients atteints d'une glomérulonéphrite pauci-immune nécrosante et d'une endocardite infectieuse à culture négative. Ceci est impératif afin d'assurer une prise de décision optimale pour la prise en charge de ces patients. Dans ce cas particulier, une suspicion clinique importante peut prévenir l'utilization inutile et potentiellement délétère d'agents immunosuppresseurs.

Importance of environmental policy on firm performance for the textile industry: A contextual study of Pakistan.

Global warming and air pollution are severe threats to humans and ecosystems. While some of these issues, particularly those on a small scale requiring low-cost behaviors, may be relieved by developing and implementing environmental policies, it is clear that legislative measures and behaviors requiring a significant degree of sacrifice are required. The goal of this research is to highlight the aspects that can contribute to improve organizational performance in Pakistan's textile industry. Through the moderating function of environmentalism, the study examines the impact of public participation, government regulation, and organizational environmental management systems (EMSs) on environmental and organizational performance The findings show that public participation, government regulation, and the organizational EMS all have a significant impact on both environmental and organizational success. Data were collected via a survey questionnaire. Smart-PLS-3 was used to evaluate the data. Furthermore, if environmentalism is regarded as a moderator, the overall influence on organizational performance will be greater. Public participation, government regulations, and an organization's EMS are all seen to have a substantial influence on both environmental and organizational success.

The Role of Transformational Leadership on Firm Performance: Mediating Effect of Corporate Sustainability and Moderating Effect of Knowledge-Sharing.

The primary purpose of the research is to investigate the mediating role of corporate sustainability in the relationship between the impacts of transformational leadership on the performance of firms. This study also aimed to investigate the moderating role of knowledge-sharing on the relationship of transformational leadership with corporate sustainability. Respondents of the study were the top management of large Chinese automobile sectors, such as Shanghai Automotive Business Corporation (Group), China FAW Group Corporation, Dongfeng Motor Co., Ltd., Beijing Automotive Group Co., Ltd., and China North Industries Group Corporation. These are the companies with the biggest market share in the automobile manufacturing industry in China. The data was gathered by using a self-administrative survey questionnaire from 198 individuals operating in different automobile industries in different sectors of China. The data were analyzed using structural equation modeling (SEM) through the Smart PLS 3.3.2 software. The results of this study revealed that transformational leadership has a positive and significant effect on the performance of the firm. Corporate sustainability has a significant positive mediating role in the association of transformational leadership and firm performance. Findings indicated that knowledge-sharing also has a positive moderating role in the association between transformational leadership and firm performance. The findings of this study contribute to the body of knowledge and show that leadership style has a significant effect on firm performance and that knowledge-sharing culture in firms is essential for better performance of the firm. Furthermore, firms may improve their performance by improving their sustainability and by creating knowledge-sharing culture. The findings are important, particularly in connection with a developed country like China. The findings have important insights for various stakeholders, i.e., government, regulatory bodies, practitioners, academia, industry, and researchers.

The Challenges of Diagnosing Nondilated Obstructive Uropathy: A Case Report.

Rationale: Nondilated obstructive uropathy (NDOU) is a rare cause of acute renal failure reported in less than 5% of cases of obstructive uropathy. It is typically associated with intrapelvic malignancies and diseases causing retroperitoneal lymphadenopathy and retroperitoneal fibrosis. As these conditions may prevent radiographic dilation of the collecting system, the diagnosis of NDOU may be missed by usual diagnostic testing. Presenting concerns of the patient: We present a case of acute anuric renal failure in a middle-aged woman with metastatic breast cancer associated with abdominal and retroperitoneal lymphadenopathy. Acute kidney injury was initially deemed secondary to drug-induced acute tubular necrosis (ATN) from bisphosphonate; however, there remained a high clinical suspicion of NDOU due to the presence of enlarged retroperitoneal lymph nodes on CT abdomen and pelvis with concerns for encasement of bilateral renal pelvic regions and ureters. Diagnoses: The patient underwent a retrograde pyelogram which demonstrated questionable narrowing bilaterally at the level of the renal pelvices. This led to an even stronger clinical suspicion of NDOU and urology service was consulted for evaluation. Intervention: Bilateral ureteral stents were placed by urology which led to robust urine output and rapid reversal of renal failure over the next 24 to 48 hours. Outcomes: Despite 2 weeks of anuria and hemodialysis, this patient's creatinine came back to her baseline. She was able to discontinue hemodialysis and her creatinine stabilized at 88.4 µmol/L (1 mg/dL). Teaching points: Nondilated obstructive uropathy is rare but important diagnosis that requires a high clinical suspicion in the appropriate clinical scenario. The lack of dilatation is believed to be related to encasement of the collecting system by tumor, fibrosis, or as in our case metastatic retroperitoneal lymphadenopathy. As this diagnosis cannot be overlooked, aggressive direct visualization or even intervention with internal or external stenting may be required to both diagnose and treat this condition.

Justification: L'uropathie obstructive sans dilatation (UOSD) est une cause rare d'insuffisance rénale aiguë (IRA) rapportée dans moins de 5 % des cas d'uropathie obstructive. Elle est généralement associée à des tumeurs malignes intrapelviennes et de maladies entraînant une lymphadénopathie rétropéritonéale et une fibrose rétropéritonéale. Ces conditions pouvant empêcher la dilatation radiographique du système collecteur, il arrive que le diagnostic de l'UOSD soit manqué lors des tests de diagnostic habituels. Présentation du cas: Nous présentons un cas d'IRA anurique chez une femme d'âge moyen atteinte d'un cancer du sein métastatique associé à une lymphadénopathie abdominale et rétropéritonéale (LAR). L'IRA avait initialement été considérée comme secondaire à une nécrose tubulaire aiguë induite par le bisphosphonate. La présence de ganglions lymphatiques rétropéritonéaux hypertrophiés sur la tomographie de l'abdomen et du bassin a toutefois soulevé un doute clinique d'UOSD; une obstruction des régions bilatérales du bassinet rénal et des uretères a été soupçonné. Diagnostic: La patiente a subi un pyélogramme rétrograde qui a montré un rétrécissement bilatéral suspect au niveau des bassinets rénaux, ce qui a soulevé un doute clinique encore plus important quant à la présence d'une UOSD. Le service d'urologie a été consulté pour évaluation. Intervention: Des endoprothèses urétérales ont été insérées bilatéralement par urologie. L'intervention a entraîné une forte production d'urine et la disparition de l'insuffisance rénale dans les 24 à 48 heures suivantes. Résultats: Malgré deux semaines d'anurie et d'hémodialyse, le taux de créatinine de la patiente est retourné à sa valeur initiale. La patiente a pu interrompre l'hémodialyse et son taux de créatinine s'est stabilisé à 88,4 micromoles/L (1 mg/dl). Enseignements tirés: Le diagnostic de l'UOSD est rare, mais important, car il requiert un doute clinique élevé dans le scénario clinique approprié. On pense que l'absence de dilatation pourrait être liée à l'obstruction du système collecteur rénal par une tumeur ou en raison d'une fibrose ou, comme ici, d'une lymphadénopathie rétropéritonéale métastatique. Puisque le diagnostic de l'UOSD ne doit pas être négligé, une visualisation directe plus poussée et l'insertion d'une endoprothèse interne ou externe pourraient s'avérer nécessaires pour diagnostiquer et traiter cette affection.

Toxic Epidermal Necrolysis Secondary to Metronidazole.

Hypersensitivity reactions occur when a host exhibits an inappropriate or exaggerated response to allergens. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of such exaggerated responses to various drugs or illnesses. Both conditions affect the skin and mucosal surfaces of the oral cavity, urethra, and conjunctiva to varying degrees. TEN involves more than 30% of the total body surface area as opposed to SJS with less than 10% involvement. Skin biopsy is considered the gold standard for diagnosis; however, obtaining appropriate clinical context at presentation with the history of a potential offending drug can help diagnose the condition in situations where skin biopsy is not feasible. Metronidazole has been rarely reported as the offending agent for TEN/SJS with only two previously reported cases in the literature. We present the third case of TEN secondary to metronidazole and discuss the potential mechanism of action of metronidazole along with its common side effects. Our case adds to the existing literature of this rare clinical presentation and highlights the importance of the judicious use of metronidazole in clinical practice.

Gitelman Syndrome: A Rare Cause of Seizure Disorder and a Systematic Review.

Gitelman syndrome is one of the few inherited causes of metabolic alkalosis due to salt losing tubulopathy. It is caused by tubular defects at the level of distal convoluted tubules, mimicking a thiazide-like tumor. It usually presents in late childhood or in teenage as nonspecific weakness, fatigability, polyuria, and polydipsia but very rarely with seizures. It is classically associated with hypokalemia, hypomagnesemia, hypocalciuria, hyperreninemia, and hyperaldosteronism. However, less frequently, it can present with normal magnesium levels. It is even rarer to find normomagnesemic patients of GS who develop seizures as the main complication since hypomagnesemia is considered the principal etiology of abnormal foci of seizure-related brain activity in GS cases. Interestingly, patients with GS are oftentimes diagnosed during pregnancy when the classic electrolyte pattern consistent with GS is noticed. Our case presents GS with normal serum magnesium in a patient, with seizures being the main clinical presentation. We also did a comprehensive literature review of 122 reported cases to show the prevalence of normal magnesium in GS cases and an overview of clinical and biochemical variability in GS. We suggest that further studies and in-depth analysis are required to understand the pathophysiology of seizures in GS patients with both normal and low magnesium levels.

Successful recovery and allogeneic stem cell transplant following chemotherapy-induced severe cardiomyopathy: literature review of management and prognostic factors.

Chemotherapy-induced cardiomyopathy is one of the major possible hazards that can result from potential cardiotoxic agents while treating cancer. Prognostic risk factors include the rate of drug administration, history of hypertension, female gender, extremes of age, previous history of mediastinal irradiation, cumulative dose and pre-existing heart disease. Close monitoring of the patients, timely diagnosis, use of well-known biomarkers including cardiac troponins, NT-ProBNP and imaging studies like 2D Echo or cardiac MRI are essential. Emerging biomarkers include carbonyl reductases (CBR1 and CBR3), aldo-keto reductases (AKR, type 1A1, 1C3, 7A2) and topoisomerase2ß (Top2ß). ß blockers and ACE inhibitors have not only been shown to slow down the progression of cardiac dysfunction but also produce symptomatic improvement. Our case report describes a patient with acute myeloblastic leukaemia who developed severe cardiomyopathy acutely after starting the anthracycline-based regimen. Nevertheless, with timely intervention her symptoms improved and subsequently she successfully received allogeneic stem cell transplantation.

Haemophagocytic lymphohistiocytosis (HLH): a rare but potentially fatal association with Plasmodium vivax malaria.

Haemophagocytic lymphohistiocytosis (HLH) is a potentially fatal syndrome that is caused by an abnormal activation of the immune system. It can present as the primary syndrome or occur secondary to a variety of conditions such as malignancy, autoimmune diseases and infections. We present a case of a man who developed HLH secondary to Plasmodium vivax infection. He presented with symptoms of fever, chills and myalgias. Physical examination revealed significant hepatosplenomegaly. The presence of pancytopaenia, elevated ferritin levels and haemophagocytosis on bone marrow biopsy confirmed the diagnosis of HLH (based on HLH-2004 criteria). There was a significant improvement after the initiation of intravenous antimalarials. No relapses were documented on follow-up. It is imperative that physicians should promptly recognise and treat this rare condition, as a timely intervention can be lifesaving.

Idiopathic sclerosing encapsulating peritonitis presenting as a right iliac fossa mass in a teenaged girl.

Sclerosing encapsulating peritonitis (SEP) is a rare peritoneal condition characterised by a firm and thick membrane that encases a part of or the whole of the small intestine. It can be idiopathic or secondary to a variety of conditions. It usually presents as an acute or subacute small bowel obstruction, however, the presentation can vary. It may be diagnosed by radiology, although definitive diagnosis is by laparoscopy or laparotomy. It is treated by excision of the covering membrane. We report a case of a teenaged girl who presented with abdominal pain and a palpable mass in the right iliac fossa. The patient underwent emergency laparotomy after her work up was inconclusive, and was found to have a case of SEP. The distal ileum and the sigmoid colon appeared to be covered by a thick membrane, which was excised. Follow-up of the patient was unremarkable.