ABSTRACT
BACKGROUND: Previous studies suggest that semicircular canal dehiscences (SCDs) have a developmental origin. OBJECTIVE: We hypothesized that if SCDs originate during development, incidence of radiographic SCDs in young children will be higher than in adults. MATERIALS AND METHODS: Thirty-four temporal bone HRCTs of children younger than 2 years and 40 temporal bone HRCTs of patients older than 18 years were reformatted and re-evaluated for presence of SCD or canal thinning. Results were compared with indications for HRCT and clinical information. RESULTS: SCDs were detected in 27.3% of children younger than 2 years of age (superior, 13.8%; posterior, 20%) and in 3% of adults (P < 0.004). Of children with one radiographic dehiscence, 55.6% had multiple and 44% had bilateral SCDs on HRCT. No lateral canal SCDs were present. Thinning of bone overlying the semicircular canals was found in 44% of children younger than 2 years and 2.5% of adults (P < 0.0001). CONCLUSION: SCDs are more common on HRCTs of very young children. This supports the hypothesis that SCDs originate from discontinuation of bone deposition/maturation. However, SCDs on imaging do not necessarily correlate with canal dehiscence syndrome and should therefore be interpreted carefully.
Subject(s)
Labyrinth Diseases/diagnostic imaging , Labyrinth Diseases/epidemiology , Semicircular Canals/diagnostic imaging , Temporal Bone/diagnostic imaging , Tomography, X-Ray Computed/statistics & numerical data , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , New York City/epidemiology , Prevalence , Radiographic Image Enhancement/methods , Risk AssessmentSubject(s)
Anti-Inflammatory Agents/administration & dosage , Antiviral Agents/administration & dosage , Auditory Threshold/drug effects , Glucocorticoids/administration & dosage , Hearing Loss, Sudden/drug therapy , Anti-Inflammatory Agents/adverse effects , Antiviral Agents/adverse effects , Audiometry, Pure-Tone , Dose-Response Relationship, Drug , Drug Therapy, Combination , Evidence-Based Medicine , Glucocorticoids/adverse effects , Hearing Loss, Sudden/etiology , Humans , Randomized Controlled Trials as TopicABSTRACT
Sudden sensorineural hearing loss (SSNHL) is commonly encountered in audiologic and otolaryngologic practice. SSNHL is most commonly defined as sensorineural hearing loss of 30 dB or greater over at least three contiguous audiometric frequencies occurring within a 72-hr period. Although the differential for SSNHL is vast, for the majority of patients an etiologic factor is not identified. Treatment for SSNHL of known etiology is directed toward that agent, with poor hearing outcomes characteristic for discoverable etiologies that cause inner ear hair cell loss. Steroid therapy is the current mainstay of treatment of idiopathic SSNHL in the United States. The prognosis for hearing recovery for idiopathic SSNHL is dependent on a number of factors including the severity of hearing loss, age, presence of vertigo, and shape of the audiogram.
