[The action of high temperature on beta-adrenoreceptor activity and catecholamine synthesis]. / Deistvie vysokoi temperatury na aktivnost' beta-adrenoretseptorov i sintez katekholaminov.

Hyperthermia and overheating of the rat isolated organs induce significant changes of the binding of receptors' specific blockers and catecholamine synthesis. One of the main mechanisms of the organism response to the temperature actions involves a local rearrangement in intensity of different stages of the adrenergic process. Possible significance of these changes in the hypothalamus for synchronisation of the organism's response to extreme temperature effects, is discussed.

[The characteristics of the adrenergic reaction of the portal vein in the rat liver]. / Kharakteristika adrenergicheskoi reaktsii vorotnoi veny pecheni krysy.

Adrenergic response to noradrenaline and specific agonists of alpha- and beta-adrenoceptors phenylephrine and isopropylnoradrenaline, as well as the effect of the alpha-adrenoceptors blockers on the functional state of beta-adrenoceptors and vice versa, were studied in the rat isolated portal vein. Functional interaction between alpha- and beta-adrenoceptors was manifested in a change of alpha-receptors when beta-receptors were blocked, and a change of reaction of beta-receptors when the alpha ones were blocked. The blockade of specific receptors seems to evoke conformational changes of cell membrane, thus modulating the affinity to the agonist of the receptors of the other type.