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[Variations of HBD-2 and TLR-2 gene expression in patients presenting with lichen ruber planus under effect of ultraviolet irradiation].
Shakhnovich, A A; Kruglova, L S.
Vopr Kurortol Fizioter Lech Fiz Kult ; (3): 34-6, 2011.
Article in Russian | MEDLINE | ID: mdl-21834467

ABSTRACT

The combination of narrow-band range UV-A (311 nm) and middle/broad-band UV-B (320-400 nm) irradiation was shown to significantly reduce manifestations of objective and subjective symptoms in the patients presenting with lichen ruber planus. Moreover, it promoted elimination ofdisbalance between characteristics of congenital immunity and normalization of HBD-2 and TLR-2 gene expression.


Subject(s)
Gene Expression Regulation/radiation effects , Lichen Planus/metabolism , Lichen Planus/therapy , Toll-Like Receptor 2/biosynthesis , Ultraviolet Rays , Ultraviolet Therapy , beta-Defensins/biosynthesis , Adult , Female , Gene Expression Regulation/immunology , Humans , Immunity, Innate/radiation effects , Lichen Planus/immunology , Male , Middle Aged , Toll-Like Receptor 2/immunology , beta-Defensins/immunology
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