ABSTRACT
Status of the cell-mediated, humoral immunity, and nonspecific defense factors were examined before and after specific therapy in 40 homosexuals suffering from secondary relapsing and latent early syphilis. The findings evidence that changes in the cell-mediated immunity of homosexual syphilitics essentially differ from those in heterosexuals with syphilis: decreased count of T-helpers and elevated one of T-suppressors evidence impaired ratio of T-lymphocyte subpopulations and immunoregulatory cell imbalance. A significantly increased level of C4 complement component was observed, evidencing a deficiency of the complement system. These data call for the development of a scheme of immunocorrective therapy for homosexuals suffering from syphilis.
Subject(s)
Homosexuality , Syphilis/immunology , Adolescent , Adult , Antibody Formation/immunology , B-Lymphocytes/immunology , Humans , Male , Middle Aged , Penicillin G/administration & dosage , Recurrence , Sexual Behavior , Syphilis/drug therapy , Syphilis, Latent/drug therapy , Syphilis, Latent/immunology , T-Lymphocytes/immunologyABSTRACT
A total of 159 homosexuals suffering from various forms of syphilis, aged 17 to 71, were screened for chlamydial antigen with the use of fluorescent monoclonal antibodies. Asymptomatic urogenital chlamydiosis was detected in 33 of 107 (30.8 percent) homosexual syphilitics. In 52 patients the material was collected simultaneously from the throat, urethra, and rectum; Chlamydia were detected in 71.2 percent of these.
Subject(s)
Chlamydia trachomatis/isolation & purification , Homosexuality , Syphilis/microbiology , Adolescent , Adult , Aged , Bisexuality/statistics & numerical data , Chlamydia Infections/epidemiology , Chlamydia Infections/microbiology , Homosexuality/statistics & numerical data , Humans , Male , Middle Aged , Moscow/epidemiology , Pharynx/microbiology , Rectum/microbiology , Syphilis/epidemiology , Syphilis, Latent/epidemiology , Syphilis, Latent/microbiology , Urethra/microbiologyABSTRACT
Seven cases of a combined course of syphilis ad HIV infection are described. All the patients are men, homo- and bisexuals. No apparent clinical features of syphilis in these patients were detectable. Recommendations on the strategy of syphilis treatment in patients with HIV infection are given.