Subject(s)
Accidents , Nuclear Reactors , Occupational Exposure , Radioactive Pollutants , Humans , Radiation Dosage , UkraineABSTRACT
Mice (CBAxC57BL) F of both sexes were exposed within the 10 km zone of Chernobyl nuclear power station. Genetic damage of phone chronic effect of increased radiation in exposed adult mice and in the course of embryogenesis was studied. The total absorbed radiation doses in testes varied from 1.85 to 0.42 Gy in embryos and from 3.4 to 2.7 Gy in adult males. Increase of dominant lethal mutations (DLM) and abnormal sperm heads (ASH) was only observed right after the end of exposure of adult males. The yield of reciprocal translocations (RT) in these males was relatively low. Among the males exposed at the stage of early embryogenesis, 4 heterozygotes for RT were revealed. In other males of this group the RT yield was low.
Subject(s)
Mutation , Spermatozoa/radiation effects , Translocation, Genetic/radiation effects , Animals , Embryo, Mammalian/radiation effects , Female , Genes, Lethal , Male , Mice , Mice, Inbred C57BL , Mice, Inbred CBA , Testis/radiation effectsABSTRACT
A study was made of the incidence of genetic damage to germ cells of male mice taken from or exposed within the thirty-kilometer zone of Chernobyl, the contaminated no-man's-land around the reactor that failed. At all contamination levels mouse spermatocytes exhibited reciprocal translocations, a relatively low frequency of which increased with increasing dose rate. Heterozygotes, with respect to reciprocal translocations (5%), were found among males exposed to enhanced radiation background as early embryos.