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Am J Emerg Med ; 34(4): 764.e5-7, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26439093

ABSTRACT

We report a case of superior mesenteric artery thrombosis after the abrupt discontinuation of rivaroxaban in a 59-year-old male patient. The initial presentation was of sudden onset abdominal pain, nausea, vomiting, diarrhea, and hematochezia in the setting of recently holding rivaroxaban anticoagulation for an atrial flutter ablative procedure. Imaging revealed thrombosis of the superior mesenteric artery and acute mesenteric ischemia requiring emergent surgical intervention for embolectomy. Upon exploratory laparotomy, the bowel was found to be viable, and an embolectomy with patch angioplasty was successful without complication. This case illustrates the need for emergency medicine clinician familiarity with this possible medication adverse event with rivaroxaban.


Subject(s)
Factor Xa Inhibitors/adverse effects , Mesenteric Artery, Superior , Mesenteric Ischemia/etiology , Rivaroxaban/adverse effects , Thrombosis/etiology , Factor Xa Inhibitors/therapeutic use , Humans , Male , Mesenteric Ischemia/surgery , Middle Aged , Rivaroxaban/therapeutic use , Thrombosis/surgery , Withholding Treatment
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