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Antimicrob Agents Chemother
; 50(10): 3499-500, 2006 Oct.
Article
in English
| MEDLINE
| ID: mdl-17005843
ABSTRACT
Two cohorts of four subjects requiring hemodialysis received tefibazumab (10 or 20 mg/kg). The mean elimination half-life was between 17 and 18 days, the average volume of distribution was 7.3 liters, and the average clearance was 12 ml/h for both dose groups. At a dose of 20 mg/kg of body weight, plasma levels were 88 microg/ml at 21 days.