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1.
Biol Trace Elem Res ; 129(1-3): 36-45, 2009.
Article in English | MEDLINE | ID: mdl-19066735

ABSTRACT

Zinc (Zn), copper (Cu), and selenium (Se) are well-known as essential trace elements. These elements attract a great interest, not only in the scientific world, but also in the public option. The aim of this study was to evaluate the serum Zn, Cu, and Se levels in healthy volunteers (60 females and 55 males) living in Tehran. The age (6-62 years) and sex of the subjects, as well as drug and tobacco consumption, were registered. The concentrations of these elements were determined by atomic absorption spectrometry. The serum levels of Zn, Cu, and Se in the normal population of Tehran was 0.89 +/- 0.16 mg/L, 0.95 +/- 0.20 mg/L, and 99.10 +/- 21.78 microg/L, respectively. There was no significant gender-related difference in serum Zn concentration (p < 0.15). However, a significant difference (p < 0.05) in both Cu and Se levels was observed between males and females.


Subject(s)
Antioxidants/analysis , Copper/blood , Selenium/blood , Zinc/blood , Adolescent , Adult , Child , Female , Health , Humans , Iran , Male , Middle Aged , Reference Values
2.
Biol Trace Elem Res ; 123(1-3): 14-26, 2008.
Article in English | MEDLINE | ID: mdl-18278442

ABSTRACT

Monitoring of toxic trace elements for human blood has been of interest to researchers in the fields of environmental chemistry and medical science. The amount of blood toxic elements can reflect the disease state of the person or the environment where that person resides or works. Chronic, low-level exposure to toxic metals such as lead (Pb), cadmium (Cd), and mercury (Hg) is an increasing global problem. This study focuses on obtaining the usual value of Pb, Cd, and Hg in normal human blood. These elements were determined in 61 male and 40 female volunteers resident in Tehran (Iran). The subjects were non-drug abusers and aged 6-62 years old. Procedures were developed for the collection, storage, and preanalytical treatment of samples. The lead and cadmium were determined by graphite furnace atomic absorption spectrometry, and mercury was measured by cold vapor atomic absorption spectrometry technique. The blood levels of Pb, Cd, and Hg in normal volunteers living in Tehran were 123.75 +/- 56.42, 1.82 +/- 0.67, and 8.48 +/- 4.42 microg/L. There was no significant gender-related difference in blood Cd and Hg concentrations (p < 0.06 and p < 0.41). However, the results indicated significantly higher content of Pb in blood of males compared to females (138.11 +/- 65.43 and 101.84 +/- 51.38 microg/L, respectively, p < 0.05).


Subject(s)
Cadmium/blood , Lead/blood , Mercury/blood , Adolescent , Adult , Child , Environmental Exposure , Female , Humans , Iran , Male , Middle Aged , Reproducibility of Results , Sensitivity and Specificity , Spectrophotometry, Atomic
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