ABSTRACT
Breast cancer rarely metastasizes to the endometrium. The signet-ring variety of breast cancer is very rare and has been reported to metastasize to the endometrium in only three previous reports. We present a patient with signet-ring breast carcinoma with metastasis to the endometrium. The patient presented with vaginal bleeding and was found to have wide spread metastasis. Endometrial metastasis in patients with signet-ring breast cancer usually denotes a poor prognosis.
Subject(s)
Breast Neoplasms/pathology , Carcinoma, Signet Ring Cell/diagnosis , Endometrial Neoplasms/diagnosis , Breast Neoplasms/therapy , Carcinoma, Signet Ring Cell/diagnostic imaging , Carcinoma, Signet Ring Cell/secondary , Carcinoma, Signet Ring Cell/therapy , Diagnosis, Differential , Endometrial Neoplasms/diagnostic imaging , Endometrial Neoplasms/secondary , Endometrial Neoplasms/therapy , Female , Humans , Mastectomy , Middle Aged , Tomography, X-Ray ComputedABSTRACT
Thromboembolic events have recently been reported following diverse regimens of chemotherapy for breast cancer. This is a report of a 39-year-old woman, a diagnosed case of locally advanced breast cancer, who received many regimens of chemotherapy. She presented with deep venous thrombosis 2 months after starting the cisplatinum-navelbine regimen. Protein C deficiency was the only abnormal coagulation test that normalized after cessation of chemotherapy.
