ABSTRACT
A comparative study was conducted to evaluate the therapeutic efficacy of diclofenac sodium and flurbiprofen both non-steroidal anti-inflammatory drugs (NSAIDS) in osteoarthritis. Forty patients of either sex between the ages of 35-60 years suffering from osteoarthritis of at least one knee joint minimum of eight weeks duration were included in the study. Diclofenac sodium exhibited better results by improving the signs and symptoms of osteoarthritis in both high and low doses compared to flurbiprofen. The adverse effects observed were similar in both groups.
Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Diclofenac/therapeutic use , Flurbiprofen/therapeutic use , Osteoarthritis/drug therapy , Female , Humans , MaleABSTRACT
Stress can be defined as any stimulus that creates an imbalance in the internal environment. Hypothalamus has sensors that detect changes produced in the body. Stress can cause diseases by altering immune system, cardiovascular System neurotransmitter and neuroendocrine functions. Present study is designed to evaluate the effect of stress on few biochemical parameters during swimming induced stress. Significant changes have been observed especially in lipid profile. Corticosterone was also evaluated as reliable stress marker.
